Effect of Oral Inflammatory Burden on Size and Stage of Oral Tongue Cancer.

Objective: Oral tongue squamous cell carcinoma is an aggressive life-threatening disease, the prognosis of which is affected by tumor stage and size. We retrospectively studied whether oral inflammatory burden and established tongue carcinoma etiological factors exert an impact on tumor size and stage.

Materials And Methods: Medical records of 183 subjects diagnosed with tongue carcinoma at Helsinki University Hospital were investigated.

Burden of oral diseases predicts development of excess weight in early adolescence: a 2-year longitudinal study.

Unlabelled: Dental caries, gingivitis, and excess weight are highly prevalent, interconnected chronic conditions. The association of oral health with the development of adiposity among children is sparsely addressed. We examined the association of oral health to the development of excess weight and central obesity in early adolescence during a 2-year follow-up period.

Surgical treatment of clinically infected mandibular fractures.

Purpose: To clarify reasons for infections, surgical techniques, and occurrence of postoperative surgical site complications in infected mandibular fractures.

Methods: Patients with clinically infected mandibular fracture of the dentate part without preceding surgery were studied retrospectively. Clinical infection was defined to occur if pus, abscess, or a fistula in the fracture area was present.

Survival of dental implants and occurrence of mucosal overgrowth in patients with head and neck cancer treated with/without radiotherapy and mucosal graft-two-year follow-up.

Objectives: The primary aim of the present study was to compare head and neck cancer treatment modality surgery and surgery with radiotherapy or chemoradiotherapy alone for dental implant (DI) survival. The second aim was to evaluate the prevalence of mucosal overgrowth around DI after treatment with or without mucosal grafts.

Materials And Methods: An observational retrospective study consisted of 59 patients with malignant head and neck tumors that received DI between 2015 and 2019.

Non-Surgical Site-Related Complications in Mandibular Fracture Surgery - A Problem of Elderly Patients?

Background: Scientific evidence of nonsurgical site-related complications in mandibular fracture patients is limited.

Purpose: The purpose was to measure the frequency of nonsurgical site complications in patients with mandible fractures, describe the types of complications, and identify the risk factors associated with these complications.

Study Design, Setting, Sample: A retrospective cohort study was conducted at the Helsinki University hospital between 2018 and 2021.

Oral Potentially Malignant Disorders and in Oral Tongue Squamous Cell Carcinoma Patients.

This retrospective study addressed the role of oral potentially malignant disorders and the presence of intraepithelial hyphae in the carcinogenesis of the oral tongue squamous cell carcinoma and its association with smoking, alcohol consumption, and oral inflammatory burden. The medical records of 183 subjects diagnosed with oral tongue squamous cell carcinoma at the Helsinki University Hospital were investigated. Preceding oral lichen planus, lichenoid reaction, and leukoplakia diagnosis were recorded.

Postoperative wound dehiscence in mandibular fractures.

Objective: To clarify the occurrence and causes of non-infection-related surgical wound dehiscence (SWD) in intraorally treated mandibular fractures.

Material And Methods: Patients with one or two fractures of the dentate part of the mandible treated surgically an intraoral approach were included in this retrospective study. The primary outcome variable was SWD.

Deep odontogenic infections - Computed tomography imaging-based spreading routes and risk for airway obstruction.

Purpose: This study aimed to evaluate deep odontogenic infection (DOI) spread and features utilizing head and neck computed tomography (CT) imaging.

Material And Methods: Patients with acute DOI and preoperative contrast-enhanced CT-imaging were included in the study. Infection spaces, radiological features of these infections, CT imaging-based compromised airway and patients' background factors were evaluated and associations between these and need for postoperative mechanical ventilation (MV) were reported.

Psychiatric morbidity is common in orthognathic surgery patients-a retrospective study.

Objective: The study aimed to clarify psychiatric morbidity in patients who underwent orthognathic surgery (OS) pre- and postoperatively.

Study Design: Patients ≥18 years undergoing OS were included in this retrospective study. The outcome variable was the incidence of new mild, moderate, or severe psychiatric morbidity or exacerbation of preexisting psychiatric morbidity postoperatively.

Streptococcus anginosus: a stealthy villain in deep odontogenic abscesses.

Odontogenic infections (OIs) occasionally spread to deep facial and neck tissues. Our study aimed to explore the role of Streptococcus anginous group (SAG) in these severe OIs. A retrospective study of patients aged ≥ 18 years who required hospital care for acute OI was conducted.

Severe infections after teeth removal - are we doing enough in preventing them?

Background: The present study clarified features and prehospital care in patients with severe infection after teeth removal.

Material And Methods: Patients who were hospitalized for infection following teeth removal were included in this study. Background variables and infection severity parameters were compared between patients who underwent elective and acute teeth removal prior to hospitalization.

Are there differences between dental diseases leading to severe odontogenic infections requiring hospitalization? A retrospective study.

Objectives: Common dental diseases may develop into severe odontogenic infections (OIs). This study aimed to characterize the occurrence and nature of dental diseases in OIs requiring hospitalization.

Method And Materials: Data of a total of 168 adult patients requiring hospital care for severe OI were retrospectively investigated.

Generalized infections of putative oral origin in Helsinki University Hospital in 2012 to 2017.

Objective: Bacteria entering the bloodstream through oral mucosa cause bacteremia, which can lead to septic or distant infections. The underlying factors and need for dental treatment in patients referred for oral examination because of septic infection were investigated. It was expected that general diseases and poor socioeconomic status of patients would increase the risk of bacteremia.

Triage and urgent dental care for COVID-19 patients in the Hospital District of Helsinki and Uusimaa.

Objective: This paper describes and reports the patient-specific characteristics of an urgent dental care clinic for COVID-19 infected, suspected, exposed or quarantined patients from March to December 2020 in the Hospital District of Helsinki and Uusimaa, Finland.

Material And Methods: The triage and the treatment protocol were established based on the scientific data. Patient files were evaluated from the hospital district's electronic medical record system.

Effect of Perioperative Systemic Dexamethasone on Pain, Edema, and Trismus in Mandibular Fracture Surgery: A Randomized Trial.

The authors' aim was to evaluate the effect of perioperative systemic dexamethasone (DXM) administration on postoperative pain, edema, and trismus in mandibular fracture patients. The authors conducted a prospective randomized study of 45 patients with one or 2 noncomminuted fractures of the dentate part of the mandible. All patients underwent surgery for intraoral miniplate fixation.

Effect of social distancing during the COVID-19 pandemic on the occurrence of maxillofacial fractures in a Finnish Tertiary Trauma Centre.

Objectives: To evaluate the effects of the COVID-19 pandemic on the occurrence of facial fractures in a tertiary trauma centre.

Materials And Methods: All facial fracture patients evaluated by an oral and maxillofacial surgeon during the first stage of the pandemic in spring 2020 were included in the study and compared to the corresponding periods in 2017 and 2018. Differences in age, sex, timespan from accident to diagnosis of facial fracture, injury mechanism, fracture type, treatment method, associated injuries (AIs), and alcohol consumption at the time of injury were analyzed between the forementioned time periods.

Effect of COVID-19 pandemic on orofacial and respiratory infections in ear, nose, and throat and oral and maxillofacial surgery emergency departments: a retrospective study of 7900 patients.

Objectives: The study purpose was to evaluate the effects of the COVID-19 pandemic on the rate and disease profile of orofacial and respiratory infections in oral and maxillofacial surgery (OMFS) and ear, nose, and throat (ENT) emergency units.

Materials And Methods: Records of patients with orofacial or respiratory infection, or infectious symptoms, diagnosed in the OMFS or ENT Emergency Departments of the Helsinki University Hospital, Helsinki, Finland between 1st March and 30th October 2020 and the corresponding periods in 2018 and 2019 were reviewed. The main outcome variable was the occurrence of studied infections during the evaluated periods.

Survival of primary molars with pulpotomy interventions: public oral health practice-based study in Helsinki.

Objectives: To assess long-term survival of pulpotomized primary molars and factors related to the survival of the teeth.

Materials And Methods: This retrospective longitudinal study was based on electronic dental health records of children who attended public health service. Eligible children were <12 years and had a pulpotomy procedure code in their dental treatment history.

High abundance of sugar metabolisers in saliva of children with caries.

Dental caries is a biofilm-mediated, dynamic disease with early onset. A balanced salivary microbiota is a foundation of oral health, while dysbiosis causes tooth decay. We compared the saliva microbiota profiles in children with and without caries.

Health status in patients hospitalised for severe odontogenic infections.

Objective: Previous findings refer to certain predisposing medical conditions that compound the risk of developing severe and potentially lethal acute odontogenic infections (OI). The objective of this study was to clarify this rationale and infection severity in general.

Material And Methods: Records of patients aged ≥18 years requiring hospital care for deep OI were retrospectively investigated.

Salivary Biomarkers of Oral Inflammation Are Associated With Cardiovascular Events and Death Among Kidney Transplant Patients.

Background: Triggering receptors expressed on myeloid cells (TREMs) and their ligand, peptidoglycan recognition protein 1 (PGLYRP-1), have been detected in secretions from patients with inflammatory diseases, which may lead to the formation of atherosclerotic plaques. Here, we aimed to analyze the association between salivary concentrations of soluble (s)TREM-1 and PGLYRP-1 with death and cardiovascular disease before and after kidney transplantation.

Materials And Methods: Saliva samples from 53 patients on dialysis were collected during their regular dental evaluation before treatment and after kidney transplantation.

Estimating molar-incisor-hypomineralization among 8-year-olds based on 15-year public oral health practice-based data.

A wide range in the prevalence of molar-incisor-hypomineralization (MIH) has been reported. Population-based studies are recommended. However, such studies are expensive and time-consuming.

The relationship between oral diseases and infectious complications in patients under dialysis.

Objectives: Association was investigated between oral health before dialysis and the incidence of systemic infections during dialysis. We hypothesized that low-grade systemic inflammation caused by poor oral health associates with infectious episodes in patients on dialysis, despite earlier eradication of oral infection foci.

Subjects And Methods: A total of 117 patients (46 with peritoneal and 71 with hemodialysis) were examined and treated at predialysis stage and followed up during dialysis.

Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation.

Objective: This prospective follow-up cohort study analyzed chronic kidney disease (CKD) patients' oral symptoms, health habits, and oral health-related quality of life (OHRQoL), from predialysis to posttransplantation. A simplified questionnaire method (Oral Health Quality Score, OHQS), based on these and clinical findings, was constructed and tested for identifying patients in need for referral to a dentist.

Material And Methods: Fifty-three CKD patients were followed up for a mean of 10.