Publications by authors named "Jurnie Rosius"
Purpose: To characterize the neuronal and vascular pathology in vivo and in vitro in a mouse model of radiation retinopathy.
Methods: C57Bl/6J mice underwent cranial irradiation with 12 Gy and in vivo imaging by optical coherence tomography and of relative blood flow velocity by laser speckle flowgraphy for up to 3-6 months after irradiation. Retinal architecture, vascular density and leakage and apoptosis were analyzed by histology and immunohistochemistry before irradiation or at 10, 30, 240, and 365 days after treatment.