Publications by authors named "Juria Nakano"
Article Synopsis
- Renal cell carcinoma (RCC) can spread to unusual sites, with a rare case reported of metastasis to the area behind the seminal vesicles in a 44-year-old male patient with clear cell RCC.
- After identifying the metastases during follow-up post-surgery, the patient underwent a unique treatment combining immune-oncology therapy and tyrosine kinase inhibitors (IO-TKI) that effectively reduced the lesions.
- The subsequent laparoscopic surgery removed all metastases, which were confirmed as clear cell RCC, and no further disease progression was observed two months after the operation, showcasing this treatment's potential for atypical metastatic cases.
Background/aim: To evaluate the effectiveness of magnetic resonance imaging/ultrasound (MRI-US)-guided fusion biopsy in the detection of clinically significant prostate cancer (CSPC) and analyze the clinical features of patients highly suspected of having prostate cancer (PCa) but shown to be negative in target biopsies (TB) among patients with prostate imaging reporting and data system (PI-RADS) 4 or 5 lesions on multiparametric MRI (mpMRI) evaluations.
Patients And Methods: We retrospectively evaluated all patients who underwent MRI/transrectal ultrasound (TRUS)-guided fusion biopsies at our institution between April 2018 and April 2022. All patients with at least one PI-RADS 3 or higher lesion and prostate-specific antigen (PSA) ≤20 ng/ml were enrolled in our study and subjected to TB in the region of interest (ROI).
Background: With the development of kidney-sparing surgery and neoadjuvant chemotherapy, ureteroscopic biopsy (URSBx) has become important for the management of upper tract urothelial carcinoma (UTUC).
Methods: We retrospectively analyzed data from 744 patients with UTUC who underwent radical nephroureterectomy (RNU), stratified into no ureteroscopy (URS), URS alone, and URSBx groups. Intravesical recurrence-free survival (IVRFS) was examined using the Kaplan-Meier method.
Introduction: Prostate biopsy is commonly performed using a transrectal ultrasound probe through a transrectal or transperineal approach. However, this is not possible for patients without a rectum.
Case Presentation: A 75-year-old male was referred to our hospital because of an elevated prostate-specific antigen and a suspicious prostate lesion (PIRADS 5) in the left peripheral zone.
Article Synopsis
- * Results showed that 37% of patients who had neoadjuvant chemotherapy experienced pathological downstaging, while those receiving adjuvant chemotherapy had significantly lower recurrence-free and cancer-specific survival rates.
- * The findings suggest that neoadjuvant chemotherapy may be a more effective treatment option for high-risk patients compared to adjuvant chemotherapy.