Assessment of sarcopenia and malnutrition using estimated GFR ratio (eGFRcys/eGFR) in hospitalised adult patients.

Background & Aims: The aim of our study was to clarify whether the eGFR ratio (eGFRcys/eGFR) is appropriate for evaluating muscle mass as an alternative method to bioelectrical impedance analysis (BIA). We also investigated the accuracy and usefulness of the eGFR ratio in the diagnosis of sarcopenia and malnutrition.

Methods: Serum creatinine (Cre) and cystatin C (Cys) were measured, and the eGFR ratio was calculated among 151 hospitalised patients (65 men and 86 women).

Kinetic analysis of inhibition of α-glucosidase by leaf powder from and its component iminosugars.

Unlabelled: Mulberry leaves contain iminosugars, such as 1-deoxynojirimycin (1-DNJ), fagomine, and 2--α-D-galactopyranosyl deoxynojirimycin (GAL-DNJ) that inhibit α-glucosidase. In this study, we quantified iminosugars in leaves and made the kinetic analysis in the hydrolysis of maltose by α-glucosidase. By LC-MS/MS, the concentrations of 1-DNJ, fagomine, and GAL-DNJ in the powdered leaves were 4.

[Change in Serum Levels of New Hepatic Fibrosis Marker "Mac-2 Binding Protein Glycosylation isomer (M2BPGi)" in Patients with Chronic Hepatitis C during the Treatment of Pegylated Interferon and Ribavirin].

The sustained virological response (SVR) rate in the patients with HCV has currently reached to 90% by the progression of anti-viral therapy. However, several reports demonstrated that hepatocellular carcinoma develops even in the patients with SVR. It is widely accepted that liver fibrosis plays a pivotal role in hepatocellular carcinogenesis.