Publications by authors named "Jurema T O Lima"
COVID-19 in children and adolescents has low frequency, severity, and fatality rate all over the world. A cross-sectional study was conducted to assess the epidemiological and clinical aspects of COVID-19 in patients younger than 20 years in Pernambuco (Brazil), with cases confirmed by reverse-transcriptase-PCR SARS-CoV-2 between 13 February and June 19, 2020, reported on information systems. Data regarding age (< 30 days, 1-11 months, 1-4 years, 5-9 years, 10-14 years, and 15-19 years), gender, color/race, symptoms, pregnancy or puerperium, comorbidities, hospitalization, and death were investigated.
View Article and Find Full Text PDFBackground And Objectives: The prognosis of colorectal cancer (CRC) has improved in the last decades, however, a lower overall survival persists in the elderly. The understanding of immunity changes in the elderly with CRC will allow the emergence of new treatments with higher response rates. 4-1BB and CD40L, an immune checkpoint stimulator, play an important role in T-cell responses and platelets.
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- The study focuses on classifying elderly cancer patients using machine learning (ML) algorithms and comprehensive geriatric assessments (CGA) to gauge their risk of early death.
- The research evaluated the ability of various ML models to predict mortality within six months of diagnosis, assessing a cohort of 608 patients through a combination of questionnaires related to mental health, physical activity, and overall health status.
- Results indicated that specific subsets of CGA questionnaires could effectively predict early death, often outperforming models that used the full set of questionnaires.