Publications by authors named "Juqin Bai"
The biomedical application of biodegradable polymers for addressing bone-related diseases has garnered considerable attention in recent years. Advances in material technology have expanded the repertoire of materials suitable for orthopedic implants, with nanomaterials playing a pivotal role in replicating crucial surface properties akin to natural tissues. This comprehensive review explores the evaluation of bioactive glass ceramics, shedding light on their properties and applications.
View Article and Find Full Text PDFA common malignant bone neoplasm in teenagers is Osteosarcoma. Chemotherapy, surgical therapy, and radiation therapy together comprise the usual clinical course of treatment for Osteosarcoma. While Osteosarcoma and other bone tumors are typically treated surgically, however, surgical resection frequently fails to completely eradicate tumors, and in turn becomes the primary reason for postoperative recurrence and metastasis, ultimately leading to a high rate of mortality.
View Article and Find Full Text PDFA developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials to targeted cell types, such as cancer cells. In healthcare, nanotechnology has brought about revolutionary changes in the treatment of various medical and surgical conditions, including in orthopedic. Its clinical applications in surgery range from developing surgical instruments and suture materials to enhancing imaging techniques, targeted drug delivery, visualization methods, and wound healing procedures.
View Article and Find Full Text PDFArticle Synopsis
- Orthopedic implants are widely used for bone treatment but face issues like bacterial infection, poor cell growth, and weak integration with body tissue, leading to complications.
- Nanotechnology presents solutions by using nanomaterials that enhance the durability, integration, and functionality of orthopedic implants, thereby addressing these existing drawbacks.
- The review discusses various nanotechnology-based biomaterials and their applications in drug delivery, tissue engineering, and improving implants' ability to integrate with bone, showcasing advancements in orthopedic research.
Current advancements in therapeutic approaches in orthopedic surgery: a review of recent trends.
Front Bioeng Biotechnol
February 2024
Article Synopsis
- * Key techniques include regenerative medicine (like stem cell therapy and PRP), robotic-assisted surgery for enhanced precision, and personalized medicine tailored to individual patient needs.
- * Additional developments involve telemedicine for better patient monitoring and the integration of AI and machine learning for improved diagnosis and treatment planning, resulting in better patient outcomes and reduced recovery times.
Nanotechnology-based bone regeneration in orthopedics: a review of recent trends.
Nanomedicine (Lond)
February 2024
Nanotechnology has revolutionized the field of bone regeneration, offering innovative solutions to address the challenges associated with conventional therapies. This comprehensive review explores the diverse landscape of nanomaterials - including nanoparticles, nanocomposites and nanofibers - tailored for bone tissue engineering. We delve into the intricate design principles, structural mimicry of native bone and the crucial role of biomaterial selection, encompassing bioceramics, polymers, metals and their hybrids.
View Article and Find Full Text PDFArticle Synopsis
- - The use of biodegradable polymers in treating bone diseases is gaining traction in biomedicine, aided by advancements in materials technology and the popularity of 3D printing for creating orthopedic implants.
- - 3D printing allows for the production of patient-specific orthopedic and dental implants, with many already receiving FDA approval, displaying benefits like cost-effectiveness and the ability to create complex structures.
- - There's a growing focus on using biodegradable metals like magnesium and iron in implants, addressing current limitations with traditional metals, while also exploring future challenges and possibilities in 3D printing applications in orthopedics.