The aqueous extract of Reynoutria japonica ameliorates damp-heat ulcerative colitis in mice by modulating gut microbiota and metabolism.

Ethnopharmacological Relevance: Reynoutria japonica has been utilized as a potential treatment for gastrointestinal disorders in Traditional Chinese Medicine (TCM). However, the efficacy and mechanism of its aqueous extracts on damp-heat ulcerative colitis (UC) remains unclear.

Aim Of The Study: Investigating the modulating effect of aqueous extracts of Reynoutria japonica (AERJ) on gut microbiota and fecal metabolisms in mice with damp-heat UC.