Publications by authors named "Junzhi Hou"
Article Synopsis
- * This study examines the effects of phlorizin, a natural compound, both alone and with the standard chemotherapy drug temozolomide (TMZ), finding that phlorizin significantly reduces cell growth and migration, especially when paired with TMZ.
- * Research indicates that phlorizin targets the PI3K/AKT/mTOR signaling pathway, which is vital for GBM cell survival, suggesting that phlorizin combined with TMZ could be a promising new treatment approach for this aggressive cancer.*
Background: Mounting evidence indicates that circular RNAs (circRNAs) play vital roles in human diseases, especially in cancers. However, the biological functions and underlying mechanism of circRNA fatty acid desaturase 2 (circFADS2) in cutaneous squamous cell carcinoma (CSCC) have not been reported.
Methods: The expression levels of circFADS2, microRNA-766-3p (miR-766-3p) and homeobox A9 (HOXA9) were determined by quantitative real-time PCR (qRT-PCR).