Angelica sinensis polysaccharide as potential protectants against recurrent spontaneous abortion: focus on autophagy regulation.

Introduction: Recurrent spontaneous abortion (RSA) represents a significant clinical challenge, with its underlying mechanisms yet to be fully elucidated. Despite advances in understanding, the precise pathophysiology driving RSA remains unclear. Angelica sinensis, a traditional herbal remedy, is frequently used as an adjunctive treatment for miscarriage.

Patient-Specific CBCT Synthesis for Real-time Tumor Tracking in Surface-guided Radiotherapy.

In this work, we present a new imaging system to support real-time tumor tracking for surface-guided radiotherapy (SGRT). SGRT uses optical surface imaging (OSI) to acquire real-time surface topography images of the patient on the treatment couch. This serves as a surrogate for intra-fractional tumor motion tracking to guide radiation delivery.

Predictive value of Der p 2-specific IgE for subcutaneous immunotherapy in children with allergic rhinitis.

Dermatophagoides pteronyssinus (Der p) subcutaneous immunotherapy (SCIT) has demonstrated efficacy in clinical trials of childhood allergic rhinitis (AR). Currently, there is a lack of some generally accepted biomarkers that may predict the clinical response to SCIT to eventually achieve personalized therapy. In this study, 28 children with AR received Der p SCIT for 26-30 months at baseline, and four efficacy endpoints, serum interleukin (IL)-5, periostin, Der p-specific IgE (sIgE), and Der p sIgG4, were measured by ELSIA.

Development of microsatellite markers and evaluation of the genetic diversity of the edible sea anemone (Cnidaria, Anthozoa) in China.

Carlgren, 1934 is a sea anemone with economic value in China. The wild population of has been shrinking due to overfishing and environmental pollution, which have caused price instability. In winter, the price of can reach 25 USD per kilogram.

The complete mitochondrial genome of the bubble-gum coral (Octocorallia: Coralliidae) from the seamount in the tropical Western Pacific.

The complete mitochondrial genome of Li et al. 2021, a deep-sea gorgonian inhabiting at 858 m in Caroline Ridge, was obtained in this study. The length of the mitochondrial genome is 19,018 bp with 14 protein coding genes, one transfer RNA (tRNA-Met) and two ribosomal RNA genes contained in this circular molecule.

Analysis of Risk Factors of Sarcopenia in Patients with Maintenance Hemodialysis and Its Correlation with Emotional Status and Quality of Life.

Objective: Sarcopenia is more common in maintenance hemodialysis (MHD) patients, and the aim of this study is to analyze the risk factors associated with sarcopenia in MHD patients, along with its correlation to emotional status and quality of life.

Methods: This is a cross-sectional cohort study. A total of 111 MHD patients who were treated in the Department of Nephrology of our hospital were selected as the study subjects by convenience sampling.

The Association Between Elevated Myocardial Injury-Related Biomarker (TnI) and Increased Mortality in Patients With Severe Fever With Thrombocytopenia Syndrome.

Objectives: The objective of this study was to investigate the dynamic profiles of myocardial injury biomarkers and their association with mortality in patients with severe fever with thrombocytopenia syndrome (SFTS).

Design: A retrospective cohort study.

Settings: Union Hospital in Wuhan, China.

Proteomics analysis of plasm exosomes in early pregnancy among normal pregnant women and those with antiphospholipid syndrome.

Introduction: Antiphospholipid syndrome (APS) is an autoimmune disorder associated with thrombosis and adverse obstetric outcomes. Early diagnosis and intervention can improve pregnancy outcomes to some extent, but current results are unsatisfactory. Exosomes, containing biomacromolecules relevant to reproduction, play essential roles in pregnancy.

Possible contributions of fibrogenesis to recurrent miscarriages - A transcriptome analysis.

Recurrent miscarriages (RM) generally refer to two or more consecutive pregnancy losses. The risk of miscarriages grows with its frequency of occurrences, so as the future obstetric complications or longer-term health problems for patients. Most previous researches sought to discover the etiology of RM by making comparisons between patients with RM and fertile women.

The complete mitochondrial genome of an economic sea anemone () in the East China Sea.

Carlgren, 1934 (Actiniidae, Actiniaria) is an edible sea anemone in China. Their wild population has intensively decreased in recent years due to overharvesting. In this study, the complete mitochondrial genome of this economic species collected in the coast of Zhejiang, China is sequenced and obtained using high throughput methods.

Edge-Enriched Molybdenum Disulfide Ultrathin Nanosheets with a Widened Interlayer Spacing for Highly Efficient Gaseous Elemental Mercury Capture.

Transition metal sulfides have exhibited remarkable advantages in gaseous elemental mercury (Hg) capture under high SO atmosphere, whereas the weak thermal stability significantly inhibits their practical application. Herein, a novel ,-dimethylformamide (DMF) insertion strategy via crystal growth engineering was developed to successfully enhance the Hg capture ability of MoS at an elevated temperature for the first time. The DMF-inserted MoS possesses an edge-enriched structure and an expanded interlayer spacing (9.

Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling.

Objectives: To explore the ability and underlying molecular mechanisms involved in the protective effects of Baicalin (BA) against L-Glutamate-induced mouse hippocampal neuron cell line HT-22.

Materials And Methods: The cell injury model of HT-22 cells was induced by L-glutamate, and cell viability and damage were detected by CCK-8 and LDH assays. Generation of intracellular reactive oxygen species (ROS) was measured by DCFH-DA fluorescence method.

Local Linearity Analysis of Deep Learning CT Denoising Algorithms.

The rapid development of deep-learning methods in medical imaging has called for an analysis method suitable for non-linear and data-dependent algorithms. In this work, we investigate a local linearity analysis where a complex neural network can be represented as piecewise linear systems. We recognize that a large number of neural networks consists of alternating linear layers and rectified linear unit (ReLU) activations, and are therefore strictly piecewise linear.

Liver Function Derangement in Patients with Severe Fever and Thrombocytopenia Syndrome.

Background And Aims: Patients with severe fever with thrombocytopenia syndrome (SFTS) commonly show liver function impairment. This study aimed to characterize the liver function indices in SFTS patients and investigate their association with mortality.

Methods: Clinical information and laboratory results of 459 laboratory-confirmed SFTS patients, including 78 deceased and 381 surviving patients, were retrospectively analyzed.

Controllable Disordered Copper Sulfide with a Sulfur-Rich Interface for High-Performance Gaseous Elemental Mercury Capture.

Copper sulfide (CuS) has received increasing attention as a promising material in gaseous elemental mercury (Hg) capture, yet how to enhance its activity at elevated temperature remains a great challenge for practical application. Herein, simultaneous improvement in the activity and thermal stability of CuS toward Hg capture was successfully achieved for the first time by controlling the crystal growth. CuS with a moderate crystallinity degree of 68.

Formation of sulfur oxide groups by SO and their roles in mercury adsorption on carbon-based materials.

The presence of SO display significant effect on the mercury (Hg) adsorption ability of carbon-based sorbent. Yet the adsorption and oxidation of SO on carbon with oxygen group, as well as the roles of different sulfur oxide groups in Hg adsorption have heretofore been unclear. The formation of sulfur oxide groups by SO and their effects on Hg adsorption on carbon was detailed examined by the density functional theory.

Practical workflow for arbitrary non-circular orbits for CT with clinical robotic C-arms.

Non-circular orbits in cone-beam CT (CBCT) imaging are increasingly being studied for potential benefits in field-of-view, dose reduction, improved image quality, minimal interference in guided procedures, metal artifact reduction, and more. While modern imaging systems such as robotic C-arms are enabling more freedom in potential orbit designs, practical implementation on such clinical systems remains challenging due to obstacles in critical stages of the workflow, including orbit realization, geometric calibration, and reconstruction. In this work, we build upon previous successes in clinical implementation and address key challenges in the geometric calibration stage with a novel calibration method.

Data-dependent Nonlinearity Analysis in CT Denoising CNNs.

Recent years have seen the increasing application of deep learning methods in medical imaging formation, processing, and analysis. These methods take advantage of the flexibility of nonlinear neural network models to encode information and features in ways that can outperform conventional approaches. However, because of the nonlinear nature of this processing, images formed by neural networks have properties that are highly data-dependent and difficult to analyze.

Performance Assessment Framework for Neural Network Denoising.

The proliferation of deep learning image processing calls for a quantitative image quality assessment framework that is suitable for nonlinear, data-dependent algorithms. In this work, we propose a method to systematically evaluate the system and noise responses such that the nonlinear transfer properties can be mapped out. The method involves sampling of lesion perturbations as a function of size, contrast, as well as clinically relevant features such as shape and texture that may be important for diagnosis.

Histiocytic Necrotizing Lymphadenitis with Cupriavidus Pauculus Infection in a Patient with Graves Hyperthyroidism: A Case Report.

Histiocytic necrotizing lymphadenitis (HNL) is a self-limiting inflammatory disease presenting with fever and cervical lymphadenopathy. However, no case of HNL with confirmed bacterial infection has been reported. A 38-year-old man was admitted to our hospital owing to an intermittent fever from 8 days.

Assessment of Boundary Discrimination Performance in a Printed Phantom.

Printed phantoms hold great potential as a tool for examining task-based image quality of x-ray imaging systems. Their ability to produce complex shapes rendered in materials with adjustable attenuation coefficients allows a new level of flexibility in the design of tasks for the evaluation of physical imaging systems. We investigate performance in a fine "boundary discrimination" task in which fine features at the margin of a clearly visible "lesion" are used to classify the lesion as malignant or benign.

Auditory Attentional Load Modulates Audiovisual Integration During Auditory/Visual Discrimination.

Attention modulates numerous stages of audiovisual integration, and studies have shown that audiovisual integration is higher in attended conditions than in unattended conditions. However, attentional resources are limited for each person, and it is not yet clear how audiovisual integration changes under different attentional loads. Here, we explored how auditory attentional load affects audiovisual integration by applying an auditory/visual discrimination task to evaluate audiovisual integration and a rapid serial auditory presentation (RSAP) task to manipulate auditory attentional resources.

High-resolution model-based material decomposition in dual-layer flat-panel CBCT.

Purpose: Spectral CT uses energy-dependent measurements that enable material discrimination in addition to reconstruction of structural information. Flat-panel detectors (FPDs) have been widely used in dedicated and interventional systems to deliver high spatial resolution, volumetric cone-beam CT (CBCT) in compact and OR-friendly designs. In this work, we derive a model-based method that facilitates high-resolution material decomposition in a spectral CBCT system equipped with a prototype dual-layer FPD.