Scalable Integration of High Sensitivity Strain Sensors Based on Silicon Nanowire Spring Array Directly Grown on Flexible Polyimide Films.

The growth and integration of position-controlled, morphology-programmable silicon nanowires (SiNWs), directly upon low-cost polymer substrates instead of postgrowth transferring, is attractive for developing advanced flexible sensors and logics. In this work, a low temperature growth of SiNWs at only 200 °C has been demonstrated, for the first time, upon flexible polyimide (PI) films, via a planar solid-liquid-solid (IPSLS) growth mechanism. The SiNWs with diameter of ∼146 nm can be grown into precise locations on PI as orderly array and with preferred elastic geometry.

Atomistic Probing and Identification of Point Defects and Grain Boundaries of 1H and 1T' Molybdenum Telluride Monolayer.

The substantial structural defects frequently observed in fabricated transition-metal dichalcogenide (TMD) samples inevitably affect the device performance. The molybdenum telluride (MoTe) monolayer can easily generate phase transitions between the 1H and 1T' phases due to a small energy barrier. However, distinguishing and identifying various defects during experiments is challenging.

Psychological Distress and the Needs of Family Members of Critically Ill Patients in Emergency Departments During the COVID-19 Pandemic: A Cross-Sectional Study.

Introduction: The literature highlights the importance of the needs of family members of critical patients in emergency departments. Understanding these needs helps to alleviate psychological distress and contribute to the patients' recoveries. This study aimed to examine the psychological distress and needs of family members of critical patients in emergency departments.

Temperature-dependent Raman spectroscopy and thermodynamic behaviors of energetic NTO crystal.

The vibrational and thermodynamic properties of energetic materials (EMs) are critical to understand their structure responses at finite temperature. In this work, the zero-point energy and temperature effects are incorporated into dispersion-corrected density functional theory to improve the calculated accuracy for vibrational responses and thermodynamic behaviors of 3-nitro-1,2,4-triazole-5-one (NTO). Based on temperature-dependent Raman spectroscopy, the emergence and disappearance of new peaks as well as discontinuous Raman shifts indicate the distinct changes of molecular configuration and intermolecular interactions within the temperature of 250-350 K.

Role of 8-hydroxyguanine DNA glycosidase 1 deficiency in exacerbating diabetic cardiomyopathy through the regulation of insulin resistance.

Diabetic cardiomyopathy (DCM) is a heart failure syndrome, and is one of the major causes of morbidity and mortality in diabetes. DCM is mainly characterized by ventricular dilation, myocardial hypertrophy, myocardial fibrosis and cardiac dysfunction. Clinical studies have found that insulin resistance is an independent risk factor for DCM.

Trajectory of change in perceived stress, coping strategies and clinical competence among undergraduate nursing students during clinical practicum: a longitudinal cohort study.

Background: Clinical practicum is crucial for strengthening nursing students' clinical competence. However, nursing students often experience considerable stress during clinical practicum, and so they employ coping strategies to alleviate it. There is almost no empirical evidence on the change trajectory of perceived stress, coping strategies, and clinical competence among nursing students during a one-year clinical practicum.

Optical flow-based closed-loop control of a multi-degree-of-freedom clamping-type ultrasonic motor.

Rotor speed and position detection are integral parts of the closed-loop control system for multi-degree-of-freedom (multi-DOF) ultrasonic motors. The non-contact speed detection method is important for the high-precision control of the spherical rotor. This paper proposes a closed-loop control method based on an optical flow sensor for the velocity-position control of a multi-DOF clamping-type ultrasonic motor.

Structural Characterization of Boron Sheets beyond the Monolayer and Implication for Experimental Synthesis and Identification.

The successful synthesis of quasi-freestanding bilayer borophene has aroused much attention for its superior physical properties and holds great promise for future electronic devices. Herein, we comprehensively explore six boron sheets beyond the monolayer and structurally characterize them via various methods using first-principles calculations for experimental references. On the basis of atomic models of borophenes, simulated scanning tunneling microscope (STM) images show different morphologies at different bias voltages and are explained by the partial densities of states and the height differences in the vertical direction.

Advances in the implications of the gut microbiota on the treatment efficacy of disease-modifying anti-rheumatic drugs in rheumatoid arthritis.

Alterations in the composition or function of the gut microbiota are associated with the etiology of human diseases. Drug-microbiota interactions can affect drug bioavailability, effectiveness, and toxicity through various routes. For instance, the direct effect of microbial enzymes on drugs can either boost or diminish their efficacy.

Pressure-dependent structure and electronic properties of energetic NTO crystals dominated by hydrogen-bonding interactions.

3-Nitro-1,2,4-trihydroxy-5-one (NTO), a highly potential high-performance explosive with good thermal stability and low sensitivity, has attracted much attention for its physicochemical properties in recent years. In this work, the pressure effect of the vibrational and electronic properties is investigated to understand the intermolecular interaction of NTO under hydrostatic compression. From the pressure-dependent Raman and infrared spectra, we found that the red-shifts of high-wavenumber N-H stretching modes and the discontinuous shifts of all Raman modes occur at 3 and 6 GPa, indicating an evident change of molecular configuration and intermolecular interaction upon compression.

Emerging insights into the role of ferroptosis in the pathogenesis of autoimmune diseases.

Ferroptosis, a novel type of regulated cell death mediated by iron-dependent lipid oxidation, was discovered a decade ago. Significant progress has been made in our knowledge of ferroptosis and immune dysfunction. This review covers recent advancements in the interaction of ferroptosis and the immune system, with an emphasis on autoimmune diseases.

Psychometric Properties of the Traditional Chinese Version of the Venous Leg Ulcer Quality of Life Questionnaire.

Objective: Symptoms and treatment of venous leg ulcers (VLUs) adversely impact patients' quality of life (QoL). There is no QoL tool that considers the linguistic and cultural specificities of patients with VLU in Taiwan. This study aimed to evaluate the psychometric properties of the traditional Chinese version of the Venous Leg Ulcer Quality of Life Questionnaire (VLU-QoL).

Insight into mechanochemical destruction of PFOA by BaTiO: An electron-dominated reduction process.

Perfluorooctanoic acid (PFOA) is a representative persistent organic pollutant and its disposal by mechanochemical (MC) technology emerges in recent years. However, degradation mechanism of PFOA especially rupture of C-F bonds during MC process is still unclear. Therefore, we innovatively employed barium titanate as co-milling reagent in MC system to disclose an electron-dominated reduction process.

Multicentric reticulohistiocytosis with eosinophilic gastroenteritis: An unusual relationship.

Multicentric reticulohistiocytosis (MRH) is a rare disease with poorly defined therapeutic strategies. Here, we report the case of a patient with eosinophilic gastroenteritis who developed MRH after 5 years. The patient presented with disabling and rapidly progressive polyarthralgia, eosinophilic gastroenteritis, and resistance to first-line therapies.

Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.

Cardiomyocyte apoptosis caused by fat metabolism disorder plays an essential role in the pathogenesis of diabetic cardiomyopathy (DCM). Apurinic/apyrimidinic endonuclease 1 (APE1) has multiple functions, including regulating redox and DNA repair. However, the role of APE1 in the pathogenesis of DCM remains unclear.

Effect of MoSe nanoribbons with NW30 edge reconstructions on the electronic and catalytic properties by strain engineering.

Monolayer transition metal dichalcogenides (TMDs), typical two-dimensional semiconductors, have been extensively studied for their extraordinary physical properties and utilized for nanoelectronics and optoelectronics. However, the finite samples and discontinuity in the synthesis process of TMD materials definitely induce defect edges in nanoribbons and greatly influence the device performance. Here, we systematically studied the atomic structures, energetic and mechanical stability, and electronic and catalytic properties of MoSe nanoribbons on the basis of experiments.

Genetic link between rheumatoid arthritis and autoimmune liver diseases: A two-sample Mendelian randomization study.

Background: An association between rheumatoid arthritis (RA) and autoimmune liver diseases (AILDs) was found in observational studies. However, neither the direction nor the cause-effect chain was clear. This study aimed to assess the causal associations between AILDs and RA.

Validation of the psychometric properties of the Self-Directed Learning Readiness Scale.

Aim: The aim of the study was to evaluate the psychometric properties of the Chinese version of the Self-Directed Learning Readiness Scale.

Design: A cross-sectional survey was designed.

Methods: A convenience sample of 659 participants was recruited.

Theoretical investigation of vibrational and electronic properties of HMX crystal under uniaxial compression.

Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) is a typical energetic molecular crystal with excellent detonation performance and good thermal stability, has been widely used in military and civilian purposes. In this work, the vibrational properties of HMX combined with structure and electronic properties are studied to understand its pressure response against uniaxial compressions. The calculated eigenvalues of stress tensors show significant anisotropy of intermolecular interactions.

Efficacy of a Decision Support Intervention on Decisional Conflict Related to Hepatocellular Cancer Treatment: A Randomized Controlled Trial.

The purpose of this study was to investigate the efficacy of decision support intervention on treatment knowledge, decision self-efficacy, decisional conflict, and decision satisfaction in patients with hepatocellular cancer. The study was a randomized controlled trial. In all, 69 patients with hepatocellular carcinoma (HCC) were recruited and randomly assigned to a decision support group or a control group.

Tuning photoelectron dynamic behavior of thiolate-protected MAu nanoclusters heteroatom substitution.

Heteroatom substitution of gold nanoclusters enables precise tuning of their physicochemical properties at the single-atom level, which has a significant impact on the applications related to excited states including photovoltaics, photocatalysis and photo-luminescence. To this end, understanding the effect of metal exchange on the structures, electronic properties and photoexcited dynamic behavior of nanoclusters is imperative. Combining density functional theory with time-domain nonadiabatic molecular dynamics simulations, herein we explored the effect of metal replacement on the electronic and vibrational properties as well as excited-state dynamics of ligand-protected MAu(SR) (M = Pd, Pt, Cd, and Hg) nanoclusters.

EGFR promotes the apoptosis of CD4 T lymphocytes through TBK1/Glut1 induced Warburg effect in sepsis.

Introduction: Sepsis-induced apoptosis leads to lymphopenia including the decrease of CD4 T cells thus favoring immunosuppression.

Objectives: Although epidermal growth factor receptor (EGFR) inhibitors significantly improve the survival rate of septic mice, the effect of EGFR on the function and metabolism of CD4 T cells in sepsis remained unknown.

Methods: CD4 T cells from septic mice and patients were assessed for apoptosis, activation, Warburg metabolism and glucose transporter 1 (Glut1) expression with or without the interference of EGFR activation.

[Network Meta-analysis of efficacy and safety of Chinese patent medicines in treatment of ankylosing spondylitis].

To evaluate the efficacy and safety of Chinese patent medicines in the treatment of ankylosing spondylitis(AS) by frequency network Meta-analysis. Randomized controlled trials(RCTs)of Chinese patent medicines for AS were retrieved from CNKI, Wanfang, VIP, CBM, PubMed, EMbase and Cochrane Library databases from the time of database establishment to January 2021. The quality of the included RCTs was evaluated according to the Cochrane bias risk standard, and the data was analyzed by RevMan 5.