Ensembled-SAMs for Enhanced Small Coronary Artery Segmentation in CCTA Images.

Accurate coronary artery segmentation is crucial for quantitative analysis of coronary arteries in noninvasive coronary computed tomography angiography (CCTA) images. However, current segmentation algorithms often have unsatisfactory recall due to the small size and complex morphology of coronary arteries, particularly in the distal segments. To address this issue, we introduce a new fully automated method named Ensembled-SAMs, which harnesses the strengths of the Segment Anything Model (SAM) and the no-new-U-Net (nnU-Net).

Liver damage and lipid metabolic dysregulation in adult zebrafish (Danio rerio) induced by spirotetramat.

Spirotetramat, an insecticide derived from cycloketone and extensively utilized in agricultural production, has been reported to be toxic to an array of aquatic organisms. Previous studies have indicated that spirotetramat can cause toxicity such as impaired ovarian development and apoptosis in zebrafish, but its toxicological effects on lipid metabolism and liver health in zebrafish remain unclear. In this study, we explored the effects of spirotetramat exposure on zebrafish (Danio rerio) by examining key markers of lipid metabolism, alterations in gene expression related to this process, and histological characteristics of the liver.