Publications by authors named "Junya Mizukami"
Article Synopsis
- The study aimed to analyze communication dynamics during home medical care using recorded conversations from nine clinics.
- A total of 55 conversations were examined, focusing on interactions among physicians, patients, and their companions, with patients averaging 82.9 years old.
- Findings show that discussions often included references to absent home medical professionals, indicating potential for improved interprofessional collaboration in patient care.
Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CHS. ASK1 knockout (KO) mice exhibited impaired 2,4-dinitrofluorobenzene (DNFB)-induced CHS.
View Article and Find Full Text PDFApoptosis and inflammation generally exert opposite effects on tumorigenesis: apoptosis serves as a barrier to tumour initiation, whereas inflammation promotes tumorigenesis. Although both events are induced by various common stressors, relatively little is known about the stress-induced signalling pathways regulating these events in tumorigenesis. Here, we show that stress-activated MAP3Ks, ASK1 and ASK2, which are involved in cellular responses to various stressors such as reactive oxygen species, differentially regulate the initiation and promotion of tumorigenesis.
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