Semantic Scene Completion in Autonomous Driving: A Two-Stream Multi-Vehicle Collaboration Approach.

Vehicle-to-vehicle communication enables capturing sensor information from diverse perspectives, greatly aiding in semantic scene completion in autonomous driving. However, the misalignment of features between ego vehicle and cooperative vehicles leads to ambiguity problems, affecting accuracy and semantic information. In this paper, we propose a Two-Stream Multi-Vehicle collaboration approach (TSMV), which divides the features of collaborative vehicles into two streams and regresses interactively.

A novel functionally graded bilayer membrane with excellent barrier function and osteogenesis promotion for guided bone regeneration.

Introduction: Guided bone regeneration (GBR) technology has been widely used as a reliable method to address alveolar bone defects. To improve the clinical effects of GBR approach, there have been attempts to develop barrier membranes with enhanced regenerative properties. However, modifying the material and structure of GBR membranes to integrate physicochemical properties and biological activity remains challenging.

H-BINOL-Derived Chiral η-Benzene Ligands: New Opportunities for the Ruthenium-Catalyzed Asymmetric C-H Activation.

Given the tremendous success of (p-cymene)Ru-catalyzed C-H activation over the past 20 years, the community has long been aware that the development of chiral η-benzene (Ben) ligands should be a potent strategy for achieving the attractive but incredibly underdeveloped ruthenium(II)-catalyzed asymmetric C-H activation. However, it has rarely been achieved due to the severe difficulty in developing proper chiral Ben ligands. In particular, designing chiral Ben ligands by connecting a benzene fragment to a chiral framework including benzene rings remained an unsolved challenge until this effort.

Evoking C production from electrochemical CO reduction by the steric confinement effect of ordered porous CuO.

Selective conversion of carbon dioxide (CO) to multi-carbon products (CO-to-C) at high current densities is in essential demand for the practical application of the resultant valuable products, yet it remains challenging to conduct due to the lack of efficient electrocatalysts. Herein, three-dimensional ordered porous cuprous oxide cuboctahedra (3DOP CuO-CO) were designed and synthesized by a molecular fence-assisted hard templating approach. Capitalizing on the merits of interconnected and uniformly distributed pore channels, 3DOP CuO-CO exhibited outstanding electrochemical CO-to-C conversion, achieving faradaic efficiency and partial current density for C products of up to 81.

Characterization of dental dust particles and their pathogenicity to respiratory system: a narrative review.

Objectives: Dental professionals are exposed to large amounts of dust particles during routine treatment and denture processing. This article provides a narrative review to investigate the most prevalent dust-related respiratory diseases among dental professionals and to discuss the effects of dental dust on human respiratory health.

Materials And Methods: A literature search was performed in PubMed/Medline, Web of Science, and Embase for articles published between 1990 and 2022.

Construction of a novel immune-related prognostic-predicting model of gastric cancer.

Gastric cancer (GC) is a common primary stomach tumor of the central nervous system with a poor prognosis. In this study, 274 differentially expressed immune-related genes (DEIRGs) were identified among six cell subpopulations in GSE112302 single-cell RNA sequencing (scRNA-seq) data of GC. Those DEIRGs were able to divide GC patients into three distinct subtypes with different overall survivals and tumor microenvironment.

Capacity planning in a decentralized autologous cell therapy manufacturing network for low-cost resilience.

The goals for increased patient access and fast fulfillment have motivated considerable interest in autologous cell therapy manufacturing networks having multiple and geographically distributed manufacturing facilities. However, the cost of safety manufacturing capacity to mitigate supplier disruption risk-a significant risk in the emerging cell manufacturing industry-would be lower if manufacturing is centralized. In this paper, we analyze a decentralized network that has as its objective to minimize the cost of network resilience for mitigating supplier disruption by making use of the fact that bioreactors for autologous therapy manufacturing are small enough to be relocatable.

Chiral Arene Ligand as Stereocontroller for Asymmetric C-H Activation.

Development of chiral ligands is the most fundamental task in metal-catalyzed asymmetric synthesis. In the last 60 years, various kinds of ligands have been sophisticatedly developed. However, it remains a long-standing challenge to develop practically useful chiral η -arene ligands, thereby seriously hampering the asymmetric synthesis promoted by arene-metal catalysts.

Mesoporous PdBi nanocages for enhanced electrocatalytic performances by all-direction accessibility and steric site activation.

An effective yet simple approach was developed to synthesize mesoporous PdBi nanocages for electrochemical applications. This technique relies on the subtle utilization of the hydrolysis of a metal salt to generate precipitate cores as templates for navigating the growth of mesoporous shells with the assistance of polymeric micelles. The mesoporous PdBi nanocages are then obtained by excavating vulnerable cores and regulating the crystals of mesoporous metallic skeletons.

Electrochemical diselenylation of indolizines via intermolecular C-Se formation with 2-methylpyridines, α-bromoketones and diselenides.

An efficient electrochemical system for the construction of diselenytlated indolizines from available pyridines, ketones and diselenides under undivided electrolytic conditions was developed. No external oxidants and transition-metal catalysts are needed for achieving this three-component tandem reaction realizing C-C, C-N and C-Se bond formations.

A multiscale simulation framework for the manufacturing facility and supply chain of autologous cell therapies.

Background Aims: Autologous cell therapy (AuCT) is an emerging therapeutic treatment that is undergoing transformation from laboratory- to industry-scale manufacturing with recent regulatory approvals. Various challenges facing the complex AuCT manufacturing and supply chain process hinder the scale out and broader application of this highly potent treatment.

Methods: We present a multiscale logistics simulation framework, AuCT-Sim, that integrates novel supply chain system modeling algorithms, methods, and tools.

Plumbagin Restrains Hepatocellular Carcinoma Angiogenesis by Stromal Cell-Derived Factor (SDF-1)/CXCR4-CXCR7 Axis.

BACKGROUND Anti-angiogenic therapy has recently emerged as a highly promising therapeutic strategy for treating hepatocellular carcinoma (HCC). MATERIAL AND METHODS We assessed cellular proliferation, invasion, and activation of growth factors (VEGF and IL-8) with SDF-1 induced in the hepatocellular carcinoma cell line SMMC-7721, and this progression was limited by plumbagin (PL). The human umbilical vein endothelial cell line HUVEC was co-cultured with SDF-1-induced SMMC-7721, and the expressions of CXCR7, CXCR4, and PI3K/Akt pathways after PL treatment were detected by RT-PCR and Western blot analysis.

Plumbagin ameliorates liver fibrosis via a ROS-mediated NF-кB signaling pathway in vitro and in vivo.

Aims: The purpose of this study was to investigate plumbagin (PL) on liver fibrosis in vitro and in vivo and to explore the underlying mechanisms.

Methods: Carbon tetrachloride (CCl) was used to establish a rat liver fibrosis model, primary hepatic stellate cells (HSCs) were isolated from the rat liver, and fibrosis-related indicators were detected.

Results: The results revealed that PL significantly prevented CCl-induced liver fibrosis, as evidenced by the attenuation of histopathological changes, the decrease of MDA and the increase of SOD and GSH-P X .

Sonochemical synthesis and properties of two new nanostructured silver(I) coordination polymers.

Two new Ag(I) coordination polymers (CPs), namely, Ag(L)(Htp) (1) and [Ag(L)]·(Htp)·2HO (2) were synthesized from the long flexible ligand of 1,6-bis(2-methylbenzimidazolyl)hexane (L), terephthalic acid (Htp) and different silver(I) salts using hydrothermal and sonochemical methods, These CPs were characterized by elemental analysis, IR spectra, scanning electron microscopy, single-crystal and powder X-ray diffraction analysis. 1 features a uninodal 3-connected 2D hcb layered structure, while 2 exhibits an infinite 1D linear chain and ultimately extended into 3D supramolecular framework via O-H⋯O and Ag⋯O interactions. In addition, the effect of various sonication concentrations of the initial reagents, ultrasonic time and power of ultrasound irradiation on the size and morphology of nanostructured 1 and 2 were evaluated.

Transition-metal-free regioselective C-H halogenation of imidazo[1,2-]pyridines: sodium chlorite/bromite as the halogen source.

A facile transition-metal-free regioselective halogenation of imidazo[1,2-]pyridines using sodium chlorite/bromite as the halogen source is presented. The reaction has provided an efficient method for the formation of C-Cl or C-Br bonds to synthesize 3-chloro or 3-bromo-imidazo[1,2-]pyridines which were then efficiently transformed into imidazo[1,2-]pyridine core π-systems by Suzuki-Miyaura reactions.

Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells.

Tumor occurrence and development are very complicated processes. In addition to the roles of exogenous carcinogenic factors, the body's internal factors also play important roles. These factors include the host response to the tumor and the tumor effect on the host.

Effects of fermentable dietary fiber supplementation on oxidative and inflammatory status in hemodialysis patients.

Background: Increased oxidative stress, inflammation, and malnutrition are important risk factors for cardiovascular disease in hemodialysis patients. High dietary intake in soluble fiber can decrease the elevated level of serum c-reactive protein in patients with chronic kidney disease. The aim of this study was to evaluate the effect of supplementation of dietary water-soluble fiber on oxidative and inflammatory status in hemodialysis patients.