Publications by authors named "Junxian Xu"

Introduction: Hypoglycemia is an acute complication that can appear in people with type 2 diabetes treated with drugs which are associated with a risk of hypoglycemia, and it may lead to individual's fear of hypoglycemia (FoH). FoH adversely affects diabetic self-management, psychological well-being, and quality of life, and it is associated with sleep quality. Nevertheless, this problem is often underestimated.

View Article and Find Full Text PDF

Near-fatal asthma (NFA) can lead to severe hypercapnia and sudden cardiac arrest; however, it can be reversed by extracorporeal membrane oxygenation (ECMO). We report a case of a 37-year-old male diagnosed with NFA. After fluid rehydaration, spasmolysis, and treatment with glucocorticoid and mechanical ventilation, the patient's condition improved temporarily.

View Article and Find Full Text PDF

Mucosal-associated invariant T (MAIT) cells are important in antibacterial immune responses; however, during sepsis, they are few in number and exhibit highly activated phenotypes. The relationship between MAIT cells in peripheral blood and the prognosis of sepsis is not well understood. Thus, this study aimed to examine the levels and phenotypes of MAIT cells in early sepsis, evaluate their clinical relevance, and investigate their association with patient prognosis.

View Article and Find Full Text PDF

Wood-based materials are multifunctional green and environmentally friendly natural construction materials, and are widely used in decorative building materials. For this reason, a lot of research has been carried out to develop new and innovative wood surface improvements and make wood more appealing through features such as fire-retardancy, hydrophobicity, and antibacterial properties. To improve the performance of wood, more and more attention is being paid to the functioning of the surface.

View Article and Find Full Text PDF

Wood is widely used as a construction material due to its many advantages, such as good mechanical properties, low production costs, and renewability. However, its flammability limits its use in construction. To solve the problem of wood flammability, the most common method to improve the fire safety of wood is to modify the wood by deep impregnation or surface coating with flame retardants.

View Article and Find Full Text PDF
Article Synopsis
  • Sepsis is a major cause of death in critically ill patients and is linked to acute kidney injury (AKI), but the underlying mechanisms are not fully understood.
  • This study examined the impact of endothelial dysfunction in sepsis-related AKI and evaluated the effects of a specific PI3Kγ inhibitor on kidney damage and endothelial injury in a mouse model.
  • Findings revealed that endothelial damage was significantly worse in sepsis-induced AKI, and inhibiting PI3Kγ helped protect and repair kidney endothelium through the Akt signaling pathway, suggesting new treatment targets.
View Article and Find Full Text PDF

Acute lung injury (ALI) is a life-threatening clinical condition associated with critically ill patients, and the construction of potential microRNA (miRNA) and messenger RNA (mRNA) regulatory networks will help to fully elucidate its underlying molecular mechanisms. First, we screened fifteen upregulated differentially expressed miRNAs (DE-miRNAs) and six downregulated DE-miRNAs from the Gene Expression Omnibus (GEO) database. Then, the predicted target genes of the upregulated and downregulated DE-miRNAs were identified from the miRNet database.

View Article and Find Full Text PDF

A 63-year-old man was admitted for acute left heart failure after doing farm work. He rapidly developed refractory cardiogenic shock due to a large left atrial myxoma which was found by bedside echocardiography. Venoarteriovenous extracorporeal membrane oxygenation (ECMO) was performed immediately, and the patient was transferred for further surgery with a good outcome.

View Article and Find Full Text PDF

Rationale: Extensive thrombosis in the portal venous system caused by hypereosinophilic syndrome (HES) is rare, and there is no consensus on anticoagulant and thrombolytic treatments for arteriovenous thrombosis caused by HES.

Patient Concerns: The clinical data of a patient with extensive thrombosis in his portal venous system (superior mesenteric, splenic, hepatic, and portal veins), renal artery thrombosis, and mesenteric thrombosis caused by HES with secondary gastrointestinal bleeding and intestinal necrosis were retrospectively analyzed. Before admission, his eosinophil count increased to 7.

View Article and Find Full Text PDF

Three new species of earthworms belonging to the genus Amynthas are described from Hainan Island, China. They are named Amynthas wenchangensis sp. nov.

View Article and Find Full Text PDF

Background: This study was designed to evaluate the efficacy of exchange transfusion in patients with severe imported falciparum malaria. Twelve patients who met the diagnostic criteria for severe malaria were treated with exchange transfusion 14 times according to a conventional anti-malarial treatment. This study evaluated the efficacy of exchange transfusion for severe imported falciparum malaria.

View Article and Find Full Text PDF