Publications by authors named "Junwu Cai"
Article Synopsis
- * A key bacterium that thrives on HMOs is a specific subspecies, which helps establish a healthy gut environment in infants but studies are limited due to the diverse structures of HMOs and the specific needs of different bacterial strains.
- * The review emphasizes the need for more research on how HMOs interact with gut bacteria and calls for structural analysis and clinical trials to enhance the understanding and applications of HMOs as synbiotics for improved infant development.
An insight into structure-activity relationships in subclass IIb bacteriocins: Plantaricin EvF.
Int J Biol Macromol
October 2024
Article Synopsis
- This study talks about a special protein called plantaricin EvF, which is really good at fighting germs.
- Unlike other similar proteins, it has a unique shape because it doesn't have a common structure called an α-helix.
- The researchers found that certain parts of the protein help keep it strong and stable, which is important for its ability to work against bacteria.
This study was designed to explore the different intestinal barrier repair mechanisms of () H4-2 and H9-3 with different exopolysaccharide (EPS) production in mice with colitis. The lipopolysaccharide (LPS)-induced IEC-6 cell inflammation model and dextran sulphate sodium (DSS)-induced mice colitis model were used. Histopathological changes, epithelial barrier integrity, short-chain fatty acid (SCFA) content, cytokine levels, NF-κB expression level, and intestinal flora were analyzed to evaluate the role of in alleviating colitis.
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