Self-generated single-drop microextraction enhanced aggregation-induced emission strategy based on magnetic metal-organic framework for microRNA-21 detection.

Lung cancer is one of the most common malignancies with low prevention efficiency and high mortality, so prevention and early detection are very important. In this work, we propose a magnetic metal-organic skeleton nanomaterial bound to biological nucleic acid chains in a spatially confined magnetic single-drop microextraction (SDME) system to enhance the aggregation-induced emission (AIE) effect for fluorescence detection of miRNA-21 associated with lung cancer. DNA/MOF network structure was formed, and loaded with an AIE material, 4',4''',4''''',4'''''''-(ethene-1,1,2,2-tetrayl) tetrakis-([1,1-biphenyl]-3-carboxylic acid) (HETTC), by DNA amplification reaction.

Recent Progress on In Situ Catalytic Conversion Catalysts for Oil Shale.

With the gradual depletion of oil resources, it is urgent to vigorously develop unconventional and renewable energy sources. As an unconventional resource with abundant resources, the rational and efficient development of oil shale is of great significance to alleviating the national energy crisis. The main methods of oil shale development are surface dry distillation and in situ transformation.

Thermosensing and thermal responses in plants.

Thermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.

Plutonium in sediments of the Eastern Guangdong coast-its sources and their contribution.

The Pu activities and Pu/Pu atom ratios of surface sediments from the Eastern Guangdong coast (EGDC) were determined by sector field ICP-MS in order to examine the sources of plutonium (Pu) and quantify their contributions. The Pu activities in the EGDC ranged from 0.113 to 0.

Release performance and kinetic behavior of volatile products from controlled pressure pyrolysis of oil shale in nitrogen atmosphere.

The gas injection parameters such as temperature, pressure and duration during the in-situ pyrolysis of oil shale are important factors that affect the pore evolution and product release characteristics of oil shale. This paper takes Huadian oil shale as a sample, uses pressurized thermogravimetry and pressurized fluidized bed experimental device to explore the influence of temperature, pressure and time on the evolution of pore structure under high-pressure nitrogen injection conditions, and analyzes the influence mechanism of pore structure evolution on the release and kinetic behavior of volatile products. The results show that in the range of 623-673 K, the effective oil recovery of oil shale pyrolysis under high pressure increases from 30.

Seasonal variations in carbon, nitrogen, and phosphorus of at different stand ages.

The seasonal variations in carbon (C), nitrogen (N), and phosphorus (P) at the organ level of during different season are poorly understood. In this study, the C, N, P, and their stoichiometric ratios in various organs of during the four seasons are discussed. The middle and young aged forests in central Yunnan province, China were chosen, and the contents of C, N, and P in fine roots (<2 mm), stems, needles, and branches were analyzed.

Seasonal variation in δC of Pinus. yunnanensis and Pinus. armandii at different stand ages.

Seasonal drought is common in Yunnan province, and water is the dominant factor limiting the growth of Pinus. yunnanensis and Pinus. armandii.

Characterization of genotype IV hepatitis E virus-like particles expressed in E.coli.

HEV (Hepatitis E virus) is an infectious disease transmitted between humans and animals, which poses a severe threat to the biological safety and property throughout the world. The disease is especially severe in patients with potential liver cirrhosis and women during pregnancy. There is no specific and thorough HEV treatment at present.

Release Mechanism of Volatile Products from Oil Shale Pressure-Controlled Pyrolysis Induced by Supercritical Carbon Dioxide.

The compactness of the oil shale reservoir and the complexity of the pore structure lead to the secondary reaction of kerogen in the process of hydrocarbon expulsion, which reduces the effective recovery of shale oil. In this paper, supercritical carbon dioxide was used as a heat carrier and a displacement medium. In a self-designed fluidized bed experimental system for pressure-controlled pyrolysis of oil shale, the experiments of oil shale pyrolysis under standard atmospheric pressure and 7.

Integrated Numerical Simulations and Experimental Measurements for the Sintering Process of Injection-Molded Ti-6Al-4V Alloy.

Metal injection molding (MIM) is an advanced manufacturing technology that enables the mass production of high-performance and complex materials, such as the Ti-6Al-4V alloy. The determination of the size change and deformation of the Ti-6Al-4V alloy after the sintering process is challenging and critical for quality control. The numerical simulation could be a fast and cost-effective way to predict size change and deformation, given the large degrees of freedom for the sintering process.

Optimization of Deep Learning Based Brain Extraction in MRI for Low Resource Environments.

Brain extraction is an indispensable step in neuro-imaging with a direct impact on downstream analyses. Most such methods have been developed for non-pathologically affected brains, and hence tend to suffer in performance when applied on brains with pathologies, e.g.

Correction: Temperature-sensitive foaming agent developed for smart foam drainage technology.

[This corrects the article DOI: 10.1039/D2RA04034D.].

Noradrenergic consolidation of social recognition memory is mediated by β-arrestin-biased signaling in the mouse prefrontal cortex.

Social recognition memory (SRM) is critical for maintaining social relationships and increasing the survival rate. The medial prefrontal cortex (mPFC) is an important brain area associated with SRM storage. Norepinephrine (NE) release regulates mPFC neuronal intrinsic excitability and excitatory synaptic transmission, however, the roles of NE signaling in the circuitry of the locus coeruleus (LC) pathway to the mPFC during SRM storage are unknown.

Temperature-sensitive foaming agent developed for smart foam drainage technology.

The conventional foam drainage technology needs to be defoamed, which is not convenient for its popularization and application. In view of this problem, from the point of molecular design, a temperature-responsive surfactant was designed and synthesized. In the synthetic process, polyoxyethylene alkyl ether carboxylic acid, diethanolamine and sodium chloroacetate were used as raw materials.

Stomata-pathogen interactions: over a century of research.

It has been 136 years since the description that fungal spores penetrated into a stoma, and 16 years since the concept of stomatal defense was developed. Recent advances have provided new insights into stomata-pathogen interactions. We briefly chronicle the milestone achievements and discuss new frontiers in stomata-pathogen interactions.

Spatial-temporal distribution of total organic carbon and its transportation in the Jiulong River Estuary.

Spatial and temporal distributions of total organic carbon (TOC) in the Jiulong River Estuary (JRE) were determined using data collected during three cruises in summer 2010, autumn 2010, and spring 2011. The TOC concentration influencing factors were identified, and the export fluxes were calculated. TOC concentration ranges were 0.

Distributions and impacts of plutonium in the environment originating from the Fukushima Daiichi Nuclear Power Plant accident: An overview of a decade of studies.

This paper reviews the current knowledge on plutonium (Pu) isotopic composition (the atom or activity ratios) and activity concentrations of Pu, Pu, Pu, and Pu resulting from the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in 2011. In this critical review, we document the characteristic values of Pu atom or activity ratios (fingerprints) and present their spatial distributions around the FDNPP site. Based on multiple Pu fingerprints (Pu/Pu activity ratio, Pu/Pu atom ratio, and Pu/Pu atom ratio), we clarify that Pu contamination from the FDNPP accident occurred in a restricted terrestrial area, while Pu in the Northwest Pacific Ocean is still predominately sourced from the Pacific Proving Grounds (PPG) and global fallout.

Discovery of a tricyclic farnesoid X receptor agonist HEC96719, a clinical candidate for treatment of non-alcoholic steatohepatitis.

Non-alcoholic fatty liver disease (NAFLD) is becoming the most predominant burden of chronic liver disease worldwide. Non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD, can develop into cirrhosis and hepatocellular cancer. Unfortunately, current options for therapeutic treatment of NASH are very limited.

Polysaccharide Alleviates Antibiotic-Associated Diarrhea Based on Modulating the Gut Microbiota in C57BL/6 Mice.

The present study investigated whether the purified polysaccharide from (CSP-1) had beneficial effects on mice with antibiotic-associated diarrhea (AAD). The effects of CSP-1 on gut microbiota were evaluated by 16S rRNA high-throughput sequencing. Results showed that CSP-1 increased the diversity and richness of gut microbiota.

ZIF-8 derived defect-rich nitrogen-doped carbon with enhanced catalytic activity for efficient non-radical activation of peroxydisulfate.

The non-radical oxidation processes of persulfate activation by carbon materials have shown great potential for industrial and saline wastewater treatment. Recently, metal-organic frameworks (MOFs) as an emerging precursor have been widely used for fabricating functional carbon materials. Herein, we reported ZIF-8 derived defect-rich nitrogen-doped carbon (ZCNs) via NaCl-assisted pyrolysis for efficient non-radical activation of peroxydisulfate to degrade rhodamine B (RB).

Marine polysaccharides from Gelidium pacificum Okamura and Cereus sinensis reveal prebiotic functions.

Many marine polysaccharides as prebiotics can promote host health by modulating gut microbiota. This study investigated the beneficial effects of purified marine plant-derived Gelidium pacificum Okamura polysaccharide (GPOP-1) and marine animal-derived Cereus sinensis polysaccharide (CSP-1) on normal mice by modulating gut microbiota. The composition and diversity of gut microbiota were evaluated using 16S rRNA high-throughput sequencing.

Distribution and budget of Cs in the China Seas.

Cesium-137 is one of the most abundant anthropogenic radionuclides released by atmospheric nuclear testing and nuclear accidents, and accordingly it may significantly impact the health of humans and marine environmental eco-systems. Documenting the distribution and inventory of Cs is thus a crucial task. In this study, we collected a large number of datasets with field observations of Cs in the China Seas, in order to provide an in-depth understanding of Cs budgets and distributions.

An overview of current knowledge concerning the inventory and sources of plutonium in the China Seas.

This study reviews the current understanding of the inventory and sources of plutonium (Pu) in the marine environment adjacent to China. The Pu inventory in the China Seas was found to have large spatial variations. The quantity in sediments decreases away from the shore, generally tracing the sedimentation rate distribution.

Isotopic composition and source of plutonium in the Qinghai-Tibet Plateau frozen soils.

The Pu activities and Pu/Pu atom ratios in the frozen soils of the Yellow River Source Area (YRSA) were determined to examine the Pu source and evaluate its environmental risk. The Pu activities of surface frozen soils in the YRSA, ranging from 0.053 to 0.