Publications by authors named "Junwan Lee"

Aim: We evaluated the prognostic value of serum- and cerebrospinal fluid (CSF)-ubiquitin carboxyl-terminal esterase L1 protein (UCHL1) measurements in post- post-out of hospital cardiac arrest (OHCA) patients treated with target temperature management (TTM), to predict neurologic outcome.

Methods: This was a prospective single-centre observational cohort study, conducted from April 2018 to September 2019. Serum- and CSF-UCHL1 were obtained immediately (UCHL1), 24 h (UCHL1), 48 h (UCHL1), and 72 h (UCHL1) after return of spontaneous circulation (ROSC).

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Aim: We evaluated the optimal timing of optic nerve sheath diameter (ONSD) measurement to predict neurologic outcome in post-cardiac arrest patients treated with target temperature management (TTM).

Methods: This was a prospective single-centre observational study from April 2018 to March 2019. Good outcome was defined as the Glasgow-Pittsburgh cerebral performance categories (CPC) 1 or 2, and poor outcome as a CPC between 3 and 5.

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Article Synopsis
  • The study evaluated the onset of severe blood-brain barrier (BBB) disruption in cardiac arrest patients undergoing target temperature management (TTM) using the cerebrospinal fluid/serum albumin quotient (Qa).
  • It involved 21 patients, categorized based on 3-month neurological outcomes, with a significant difference in Qa levels between good and poor outcome groups at 24, 48, and 72 hours post-return of spontaneous circulation (ROSC).
  • The findings suggest that severe BBB disruption, indicated by Qa values, occurred within the first 24 hours in patients with poor outcomes following TTM treatment.
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Aim: The optimal time to measure serum albumin concentration (SAC) to predict prognosis in cardiac arrest (CA) survivors has not been elucidated. We aimed to compare the relationships between time-related SAC, optic nerve sheath diameter (ONSD), intracranial pressure (ICP), and neurological prognosis in CA survivors.

Methods: We undertook a retrospective study examining CA patients treated with target temperature management (TTM).

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Aim: The present study aimed to compare the ventricular enhancement time between humeral intraosseous access (HIO) and brachial intravenous access (BIV) during cardiopulmonary resuscitation (CPR) in adult humans. To our knowledge, this is the first such study during CPR in adult humans.

Methods: This prospective single-centre observational cohort study assessed the medical records of patients who underwent CPR between January 2018 and March 2018.

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Incidences of brain death due to nicotine overdose by e-cigarettes have been increasing. In such cases, liver donation has been not reported because of the secondary damage to the liver due to metabolism of large amounts of nicotine. However, kidneys have been considered acceptable for transplant.

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Objective: We investigated whether patients with out-of-hospital cardiac arrest (OHCA) due to an acute myocardial infarction without cardiogenic shock required higher doses of vasopressors with low targeted temperature management (TTM) after return of spontaneous circulation.

Methods: We included consecutive comatose patients resuscitated from OHCA between January 2011 and December 2013. Patients with return of spontaneous circulation, regional wall motion abnormality on echocardiography, and coronary artery stenosis of ≥70% on percutaneous coronary artery angiography were enrolled.

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Hemothorax is not an uncommon cardiopulmonary resuscitation(CPR)–related complication. But hemothorax related to azygos vein injury (AVI) is a rare condition following blunt chest trauma, with no report of CPR-related AVI in the literature. We present a case of azygosve in rupture in a middle-aged woman after repeated chest compression during 1 hour of CPR.

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