A lumped-parameter model of the free-flooded ring transducer array.

The free-flooded ring (FFR) transducer is an extensively used ring-type acoustic transducer in underwater environments owing to its broad operating frequency bandwidth and small size. However, achieving high sound pressure levels with a single FFR transducer is often difficult, thus necessitating the construction of vertically arranged FFR transducer arrays. This study presents a comprehensive analysis of the electrical and acoustic characteristics of an FFR transducer array by considering the mutual radiation load and the effects of gaps between adjacent piezoelectric rings.

Epigenetic MicroRNAs as Prognostic Markers of Postoperative Atrial Fibrillation: A Systematic Review.

Postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery, increasing the risk for adverse outcomes such as perioperative and long-term mortality, stroke, myocardial infarction, and other thromboembolic events. Epigenetic biomarkers show promise as prognostic tools for POAF. Epigenetic changes, such as DNA methylation, histone modification, and microRNAs (miRNA), can result in altered gene expression and the development of various pathological conditions.

Yb Substitution and Ultralow Thermal Conductivity of the CaYbAlSb (0 ≤ ≤ 0.81(1)) System.

A series of Yb-substituted Zintl phases in the CaYbAlSb (0 ≤ ≤ 0.81(1)) system has been synthesized by initial arc melting and post-heat treatment, and their isotypic crystal structures were characterized by both powder and single crystal X-ray diffraction analysis. All four title compounds adopted the CaAlAs-type structure (space group , Pearson code 28, = 4).

Opioids-induced inhibition of HERG ion channels and sudden cardiac death, a systematic review of current literature.

Background: It is estimated that over 60 million individuals regularly use opioids globally, with opioid use disorder increasing substantially in the past decade. Several reports have linked sudden cardiac death, QTc prolongation, and other adverse cardiovascular outcomes with opioid use through their inhibitory effect on the human ether-a-go-go-related gene (HERG) ion channel. Therefore, understanding this underlying mechanism may be critical for risk prevention and management in prescribing opioids and treating patients with opioid dependency.

Pseudo-Hydrodynamic Flow of Quasiparticles in Semimetal WTe at Room Temperature.

Recently, much interest has emerged in fluid-like electric charge transport in various solid-state systems. The hydrodynamic behavior of the electronic fluid reveals itself as a decrease of the electrical resistance with increasing temperature (the Gurzhi effect) in narrow channels, polynomial scaling of the resistance as a function of the channel width, violation of the Wiedemann-Franz law supported by the emergence of the Poiseuille flow. Similar to whirlpools in flowing water, the viscous electronic flow generates vortices, resulting in abnormal sign-changing electrical response driven by backflow.

Reduction in Biogenic Amine Content in (Napa Cabbage) Kimchi by Biogenic Amine-Degrading Lactic Acid Bacteria.

This study was performed to mine biogenic amine (BA)-degrading lactic acid bacteria (LAB) from kimchi and to investigate the effects of the LAB strains on BA reduction in kimchi fermentation. Among 1448 LAB strains isolated from various kimchi varieties, five strains capable of considerably degrading histamine and/or tyramine were selected through in vitro tests and identified as PK08, PK05, YM20, KD15, and YM21. The selected strains were used to ferment five groups of kimchi, respectively.

740-watt level optical tap coupler using side-polished large-mode-area double clad fibers for a high power fiber laser.

We fabricated a fiber-optic directional coupler based on evanescent field coupling between side-polished large mode area (LMA) double clad fibers (DCFs) for a high power fiber laser. The tapping ratio of the fabricated coupler was measured to be - 32 dB. The fundamental mode coupled in a core of the lower side-polished fiber (SPF) was transferred to the upper SPF without clad-mode coupling.

-Type Double Doping and the Diamond-like Morphology Shift of the Zintl Phase Thermoelectric Materials: The CaASbGe (A = Na, Li; 0.06(3) ≤ ≤ 0.17(5), 0.19(1) ≤ ≤ 0.55(1), 0.13(1) ≤ ≤ 0.22(1)) System.

Five ternary and quaternary Zintl phases in the solid-solution CaASbGe (A = Na, Li; 0.06(3) ≤ ≤ 0.17(5), 0.

Effectiveness of synthetic aperture focusing and coherence factor weighting for intravascular ultrasound imaging.

Synthetic aperture focusing (SAF) and coherence factor weighting (CFW) have been used to improve the lateral resolution of ultrasound images. Although the two methods are effective for array-based ultrasound imaging, many researchers have also employed the methods for single-element-based imaging including intravascular ultrasound (IVUS) imaging. For single-element-based imaging, CFW is generally calculated from the scanlines obtained by SAF and applied to the scanline obtained after coherent summation of the SAF delayed scanlines, which is called a SAF-CFW method.

Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.

Mutations in centrosome genes deplete neural progenitor cells (NPCs) during brain development, causing microcephaly. While NPC attrition is linked to TP53-mediated cell death in several microcephaly models, how TP53 is activated remains unclear. In cultured cells, mitotic delays resulting from centrosome loss prevent the growth of unfit daughter cells by activating a pathway involving 53BP1, USP28, and TP53, termed the mitotic surveillance pathway.

Two Steps to Improve the Thermoelectric Performance of the CaYbAlInSb System.

A series of quaternary and quinary Zintl phase thermoelectric (TE) compounds, CaYbAlInSb (3.07(1) ≤ ≤ 4.88(2); 0.

The Role of as a Key Producer and Fermentation Condition as an Influencing Factor in Tyramine Accumulation in .

The study evaluated the role of in tyramine production and its response to fermentation temperature in a traditional Korean fermented soybean paste, . Tyramine content was detected in retail products at high concentrations exceeding the recommended limit up to a factor of 14. All retail products contained spp.

Magnetically Actuated Forward-Looking Interventional Ultrasound Imaging: Feasibility Studies.

Objective: Interventional ultrasound imaging is a prerequisite for guiding implants and treatment within the hearts and blood vessels. Due to limitations on the catheter's diameter, interventional ultrasonic transducers have side-looking structures although forward-looking imaging may provide more intuitive and real time guidance in treating diseased sites ahead of catheters. To address the issue, a magnetically actuated forward-looking interventional ultrasound imaging device is implemented for the first time.

2.05 kW all-fiber high-beam-quality fiber amplifier with stimulated Brillouin scattering suppression incorporating a narrow-linewidth fiber-Bragg-grating-stabilized laser diode seed source.

We experimentally demonstrate an all-fiber high-power fiber amplifier with high beam quality and a slope efficiency of 81.8%, using a fiber-Bragg-grating-stabilized laser diode as a narrow spectral linewidth (0.08 nm) seed source.

Dual-Element Intravascular Ultrasound Transducer for Tissue Harmonic Imaging and Frequency Compounding: Development and Imaging Performance Assessment.

Objective: For accurate diagnosis of atherosclerosis, the high spatial and contrast resolutions of intravascular ultrasound (IVUS) images are a key requirement. Increasing the center frequency of IVUS is a simple solution to meet this requirement. However, this leads to a reduction in imaging depth due to the frequency-dependent attenuation of ultrasound.

Layered Bismuth Oxyfluoride Nitrates Revealing Large Second-Harmonic Generation and Photocatalytic Properties.

Two novel bismuth oxyfluoride nitrates, BiOF(NO) and BiOF(NO), have been synthesized via hydrothermal reactions. Whereas BiOF(NO) crystallizes in the centrosymmetric (CS) hexagonal space group, P6/ m, BiOF(NO) crystallizes in the polar noncentrosymmetric (NCS) trigonal space group, R3. The backbones of the title compounds reveal double layered structures composed of asymmetric BiF(O/F) or BiOF polyhedra and NO trigonal planar groups.

A 40-MHz Ultrasound Transducer with an Angled Aperture for Guiding Percutaneous Revascularization of Chronic Total Occlusion: A Feasibility Study.

Complete blockage of a coronary artery, called chronic total occlusion (CTO), frequently occurs due to atherosclerosis. To reopen the obstructed blood vessels with a stent, guidewire crossing is performed with the help of angiography that can provide the location of CTO lesions and the image of guidewire tip. Since angiography is incapable of imaging inside a CTO lesion, the surgeons are blind during guidewire crossing.

A 35 MHz/105 MHz Dual-Element Focused Transducer for Intravascular Ultrasound Tissue Imaging Using the Third Harmonic.

The superharmonic imaging of tissue has the potential for high spatial and contrast resolutions, compared to the fundamental and second harmonic imaging. For this technique, the spectral bandwidth of an ultrasound transducer is divided for transmission of ultrasound and reception of its superharmonics (i.e.

Development of Dual-Frequency Oblong-Shaped-Focused Transducers for Intravascular Ultrasound Tissue Harmonic Imaging.

Tissue harmonic imaging (THI), an essential mode of commercial ultrasound imaging scanners, can provide images with high spatial and contrast resolutions. For THI, the frequency spectrum of a transducer is generally divided for the transmission of fundamental signal and the reception of its second harmonic. Therefore, it is difficult to use the THI mode for intravascular ultrasound (IVUS) imaging because typical IVUS transducers have a narrow -6-dB fractional bandwidth of about 50%.

Structure and Chemical Bonding of the Li-Doped Polar Intermetallic RE₂InLiGe₂ (RE = La, Nd, Sm, Gd; x = 0.13, 0.28, 0.43, 0.53) System.

Four polar intermetallic compounds belonging to the ₂InLiGe₂ ( = La, Nd, Sm, Gd; = 0.13(1), 0.28(1), 0.

Single and double-doping effects on the thermoelectric properties of two Zintl compounds: EuBiSn and EuKBiSn.

Two Zintl phase thermoelectric compounds of EuKBiSn (x = 0, 0.26(1); y = 0.86(2), 1.

Effect of MultiSubstitution on the Thermoelectric Performance of the CaYbSbGe (0 ≤ x ≤ 9; 0 ≤ y ≤ 3; 0 ≤ z ≤ 3) System: Experimental and Theoretical Studies.

The Zintl phase solid-solution CaYbSbGe (0 ≤ x ≤ 9; 0 ≤ y ≤ 3; 0 ≤ z ≤ 3) system with the cationic/anionic multisubstitution has been synthesized by molten Sn metal flux and arc-melting methods. The crystal structure of the nine title compounds were characterized by both powder and single-crystal X-ray diffractions and adopted the HoGe-type structure with the tetragonal space group I4/mmm (Z = 4, Pearson Code tI84). The overall isotypic structure of the nine title compounds can be illustrated as an assembly of three different types of cationic polyhedra sharing faces with their neighboring polyhedra and the three-dimensional cage-shaped anionic frameworks consisting of the dumbbell-shaped Sb units and the square-shaped Sb or (Sb/Ge) units.

Liver receptor homolog-1 regulates mouse superoxide dismutase 2.

Liver receptor homolog-1 (LRH-1) is a nuclear receptor that plays an important role in the regulation of bile acid biosynthesis, cholesterol reverse transport, steroidogenesis, and exocrine pancreatic enzyme production. In the current study, previously published data from a genome wide analysis of LRH-1 binding in the liver were re-analyzed to identify new LRH-1 targets and propose new roles for LRH-1 in the liver. Superoxide dismutase 2 (Sod2) was identified, which contains putative LRH-1 binding sites in the proximal promoter.