Evaluation of the Curative Effects of Surgical Intervention in Cases of Congenital Malformation of the Ossicular Chain in Children.

Congenital malformation of the ossicular chain results in challenges with hearing and language development in children. We aimed to analyze the clinical characteristics, prognosis, and surgical treatments of different types of congenital ossicular chain malformations in children. Eight cases (10 ears) treated between October 2019 and February 2022 were analyzed retrospectively.

[Long-term auditory monitoring in children with Alport syndrome based on different degrees of renal injury].

To investigate long-term auditory changes and characteristics of Alport syndrome（AS） patients with different degrees of renal injury. Retrospectively analyzing clinical data of patients diagnosed AS from January 2007 to September 2022, including renal pathology, genetic detection and hearing examination. A long-term follow-up focusing on hearing and renal function was conducted.

[Influence of CD4+ and CD25+ T regulatory cell on mouse bearing gastric tumor in vivo].

Objective: To investigate the influence of CD4+ CD25+ regulatory T cells(Treg cells) on mouse gastric cancer.

Methods: Treg cell in mouse spleen bearing gastric tumor was tested in different time points. Magic cell sorting(MACS) method was used to purify mouse Treg cells and the Treg cells were injected into mouse bearing gastric tumor with different dosage.