LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.

Long noncoding RNAs (lncRNAs) have been demonstrated to participate in neuroblastoma cisplatin resistance and tumorigenesis. LncRNA LINC00460 was previously reported to play a critical regulatory role in many cancer development. Nevertheless, its role in modulating neuroblastoma cisplatin resistance has not been explored till now.

Monte Carlo-transformed field expansion method for simulating electromagnetic wave scattering by multilayered random media.

We present an efficient numerical method for simulating the scattering of electromagnetic fields by a multilayered medium with random interfaces. The elements of this algorithm, the Monte Carlo-transformed field expansion method, are (i) an interfacial problem formulation in terms of impedance-impedance operators, (ii) simulation by a high-order perturbation of surfaces approach (the transformed field expansions method), and (iii) efficient computation of the wave field for each random sample by forward and backward substitutions. Our perturbative formulation permits us to solve a sequence of linear problems featuring an operator that is deterministic, and its LU decomposition matrices can be reused, leading to significant savings in computational effort.

Inguinal hernia repair by Bianchi incision in boys: a retrospective study.

Objective: Open inguinal hernia repair by Bianchi incision is a potential alternative technique for the treatment of IH. This study aims to retrospectively analyze boys with IH, who underwent open IH repair by Bianchi incision.

Methods: A total of 3300 boys (1-144 months) with IH from April 2007 to September 2015 were enrolled into this study.

[Effect of epidermal growth factor and testosterone on androgen receptor activation in urethral plate fibroblasts in hypospadias].

Objective: To investigate androgen receptor (AR) expression and the effect of epidermal growth factor (EGF) and testosterone on AR expression level.


Methods: EGF or different concentrations of testosterone were incubated with the primary urethral plate fibroblasts from patients with hypospadias. The levels of AR expression in the fibroblasts were detected by immunocytochemical assays and graphical analysis.

[EFFECTIVENESS OF ADVANCED SKIN FLAP AND V-SHAPED VENTRAL INCISION ALONG THE ROOT OF PENILE SHAFT FOR CONCEALED PENIS].

Objective: To investigate effectiveness of advanced skin flap and V-shaped ventral incision along the root of penile shaft for concealed penis in children.

Methods: Between July 2007 and January 2015, 121 boys with concealed penis were treated with advanced skin flap and V-shaped ventral incision along the root of penile shaft. The age varied from 18 months to 13 years (mean, 7.

Field enhancement and saturation of millimeter waves inside a metallic nanogap.

This paper investigates the millimeter electromagnetic waves passing through a metal nanogap. Based upon the study of a perfect electrical conductor model, we show that the electric field enhancement inside the gap saturates as the gap size approaches zero, and the ultimate enhancement strength is inversely proportional to the thickness of the metal film. In addition, no significant enhancement can be gained by decreasing the gap size further if the aspect ratio between the dimensions of the underlying geometric structure exceeds approximately 100.

Imaging of reflective surfaces by near-field optics.

We consider an imaging problem that aims to identify the profile of a reflective surface by the scattered wave measured in the near field. Potential applications include nondestructive detection of micro devices, subwavelength imaging techniques in nano-optics. When the height of the imaging target is small, the connection between the localized evanescent wave modes of the measurement and the high spatial frequency components of the structure is characterized explicitly, which leads to a natural reconstruction method with super resolution images.