Publications by authors named "Junrui Ding"
Free Radic Biol Med
November 2024
Article Synopsis
- - Psoriasis is a chronic skin condition linked to immune system dysfunction and oxidative stress, with the neonatal Fc receptor (FcRn) playing a potential role in its severity according to clinical analyses.
- - In a mouse model of psoriasis, researchers found lower levels of FcRn in affected skin, and the ferroptosis pathway was activated, suggesting that FcRn may influence this process through the STAT3/SLC7A11 signaling pathway.
- - Experiments indicated that depleting FcRn increased psoriatic lesions and ferroptosis, while inhibiting this process or activating FcRn improved symptoms, pointing to possible new treatments for psoriasis.
