Publications by authors named "Junren He"

Article Synopsis
  • This study investigates the relationship between choroidal microvasculature dropout (MvD) and retinal nerve fiber layer (RNFL) defects in patients with primary angle-closure glaucoma (PACG) compared to healthy individuals.
  • Out of 55 PACG patients, 47.3% showed MvD, which was absent in healthy controls; patients with MvD had thinner RNFL and worse visual field results.
  • The findings indicate a significant correlation between the MvD angular circumference and the severity of optic nerve injury in glaucoma, suggesting a possible vascular link in the disease's progression.
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The objectives of this study were to develop a three-dimensional acellular cartilage matrix (ACM) and investigate its possibility for use as a scaffold in cartilage tissue engineering. Bovine articular cartilage was decellularized sequentially with trypsin, nuclease solution, hypotonic buffer, and Triton x 100 solution; molded with freeze-drying process; and cross-linked by ultraviolet irradiation. Histological and biochemical analysis showed that the ACM was devoid of cells and still maintained the collagen and glycosaminoglycan components of cartilage.

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Objective: To produce a decellularized cartilage matrix (DCM) and investigate its possibility to be used as a scaffold for tissue engineering.

Methods: Fresh bovine articular cartilage from knee joints was sliced, freeze-dried and freeze-ground into fine powder, and then was treated sequentially with Trypsin, Triton X-100 and hypotonic solution for decellularization. The decellularized matrix was freeze-dried for shaping and cross-linked by UV radiation.

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Objective: To observe the effects of Xinshuai Mistura (XM) on plasma angiotensin II (Ang II), atrial natriuretic peptide (ANP) and N terminal pro- brain natriuretic peptide (Nt-proBNP) in patients with heart failure (HF).

Methods: Fifty-nine patients with HF (NYHA class II-IV) were randomly divided into two groups, the treated group treated with XM and the control group with Wuling Pulvis (WP), both on the base of captopril treatment. The treatment course was two weeks.

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