Wastewater multiplex PCR amplicon sequencing revealed community transmission of SARS-CoV-2 lineages during the outbreak of infection in Chinese Mainland.

During the COVID-19, wastewater-based epidemiology (WBE) has become a powerful epidemic surveillance tool widely used worldwide. However, the development and application of this technology in Chinese Mainland are relatively lagging. Herein, we for the first time monitored the community circulation of SARS-CoV-2 lineages using WBE methods in Chinese Mainland.

Low-frequency rTMS modulated the excitability and high-frequency firing in hippocampal neurons of the Alzheimer's disease mouse model.

Repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, holds potential for applications in the treatment of Alzheimer's disease (AD). This study aims to compare the therapeutic effects of rTMS at different frequencies on Alzheimer's disease and explore the alterations in neuronal electrophysiological properties throughout this process. APP/PS1 AD mice were subjected to two rTMS treatments at 0.

Joint Unsupervised Learning of Depth, Pose, Ground Normal Vector and Ground Segmentation by a Monocular Camera Sensor.

We propose a completely unsupervised approach to simultaneously estimate scene depth, ego-pose, ground segmentation and ground normal vector from only monocular RGB video sequences. In our approach, estimation for different scene structures can mutually benefit each other by the joint optimization. Specifically, we use the mutual information loss to pre-train the ground segmentation network and before adding the corresponding self-learning label obtained by a geometric method.

Visual Semantic Landmark-Based Robust Mapping and Localization for Autonomous Indoor Parking.

Autonomous parking in an indoor parking lot without human intervention is one of the most demanded and challenging tasks of autonomous driving systems. The key to this task is precise real-time indoor localization. However, state-of-the-art low-level visual feature-based simultaneous localization and mapping systems (VSLAM) suffer in monotonous or texture-less scenes and under poor illumination or dynamic conditions.

[A Meta-analysis on Acupuncture and Moxibustion Treatment of Schizophrenia].

Objective: To evaluate the clinical efficacy and security of acupuncture therapy combined with conventional antipsychotics in the treatment of schizophrenia.

Methods: We first comprehensively retrieved papers about acupuncture or moxibustion treatment of schizophrenia published from the time of establishment of the database to April of 2017 in Chinese databases such as Chinese National Knowledge Infrastructure(CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang, and Chinese BioMedical Literature (CBM) by using keywords "acupuncture""moxibustion""acupuncture ＋moxibustion""acupuncture ＋medication""electroacupuncture""filiform needle""scalp-acupuncture""auricular acupuncture"， etc. Then, according to the principles and methods of evidence-based medicine, papers conformed to the included standards were enrolled to Meta-analysis by using Review Manager 5.

Characterization of luminescent Vibrio campbellii LZ5 and its potential application in the detection of environmental heavy metals.

A luminescent strain was isolated and identified as Vibrio campbellii strain LZ5 by 16S rDNA analysis. It grew well in broad living conditions, and the relative fluorescence intensity was stable at pH ranging from 5 to 7.5, NaCl concentrations from 0% to 3%, KCl from 1.

Escherichia coli toxin gene hipA affects biofilm formation and DNA release.

Toxin-antitoxin (TA) systems in Escherichia coli may play a role in biofilm formation, but the mechanism involved remains debatable. It is not known whether the TA systems are responsible for extracellular DNA (eDNA) in biofilms. In this study, we investigated the function of the hipBA TA system in biofilm formation by Escherichia coli strain BW25113.