Elucidation of potential lipid precursors and formation pathways for the warmed-over flavor (WOF) in precooked Chinese stewed beef through lipid oxidation mechanisms.

The role of lipids in the formation and development of warmed-over flavor (WOF) in precooked Chinese stewed beef was investigated using lipidomics. Fourteen predominant odorants (relative odor activity value ≥1) were identified in the reheated stewed beef. A total of 1236 lipids were detected in cooked and reheated stewed beef.

Ultrasound synergized saline thawing reduces quality deterioration of Tibetan pork during thawing.

Meat quality degradation induced by highland transport emphasises the importance of efficient thawing for Tibetan pork quality. The objective of this study was to examine the impact of various thawing methods on the quality characteristics, protein oxidation, and nutrient composition of Tibetan pork. Ultrasound synergized saline thawing (UST) significantly enhanced tenderness and reduced the oxidation degree of myofibrillar protein, improving the Tibetan pork quality.

Construction of carbon dot-embedded fluorescent hydrogels based on oxidized gum arabic-gelatin Schiff base for Cr(VI) detection applications.

In this study, a novel nitrogen-doped carbon quantum dot/oxidized gum arabic-gelatin-based fluorescent probe (NAH) was prepared using gelatin (GL) and gum arabic (AG) biomolecules. The primary network structure of this hydrogel consisted of polyacrylamide (PAM), while a secondary network structure was constructed between oxidized gum arabic and gelatin through the reaction of the Schiff base, which significantly enhanced the mechanical properties, the stress and strain of NAH reached 266.47 KPa and 2175.

Comparison and elucidation of the changes in the key odorants of precooked stewed beef during cooking-refrigeration-reheating.

The key odorants contributing to the warmed-over flavor (WOF) of reheated precooked stewed beef were characterized using a sensomics approach. Overall, 36 odorants were identified, and based on flavor dilution factors, odor activity values, aroma recombination, and omission test, 11 compounds mainly derived from lipid oxidation were characterized as the key odorants contributing to the formation of WOF. In particular, 3-(methylthio)propanal, which was positively correlated with meaty aroma, was implicated in an overall increase in WOF.

Ultrasound-assisted improvement of thawing quality of Tibetan pork by inhibiting oxidation.

The challenge of meat quality degradation due to transportation difficulties in high-altitude plateaus underscores the importance of an efficient thawing process for Tibetan pork to ensure its quality. This study compared four thawing methods ultrasound thawing (UT), refrigerator thawing (RT), hydrostatic thawing (HT), and microwave thawing (MT) to assess their impact on the quality of Tibetan pork, focusing on thawing loss, tenderness, color variation, and alterations in protein secondary structure and moisture content. Additionally, the study examined the impact of thawing on the metabolites of Tibetan pork using metabolomics techniques.

Serum mir-142-3p release in children with viral encephalitis and its relationship with nerve injury and inflammatory response.

Background: Viral encephalitis (VE) is a common infectious disease of the central nervous system in children. Children with severe disease may have progressive neurological damage and even lead to death.

Aims: To assess the serum miR-142-3p levels in children with VE and the correlation between miR-142-3p and the severity and prognosis of VE.

Emulsification properties of ovalbumin-fucoidan (OVA-FUC) binary complexes.

The poor thermal stability and emulsifying properties of ovalbumin (OVA) limit its functional performance, but these limitations may be overcome by forming binary complexes. We prepared binary complexes of OVA and fucoidan (FUC) through electrostatic self-assembly and investigated the emulsifying properties of the complex by measuring the particle size, interfacial membrane thickness, potential, and stability of the emulsion prepared with camellia oil and the complex. The OVA-FUC emulsions have a thicker interfacial membrane, lower mobility, higher viscosity, and better stability compared with the OVA emulsions.

Mechanism underlying the tenderness evolution of stir-fried pork slices with heating rate revealed by infrared thermal imaging assistance.

This study aimed to explore the mechanism of cooking intensity on the tenderness of stir-fried pork slices from the perspective of the changes in temperature distribution. Infrared thermal imaging was used to monitor the distribution of temperature. Results showed that the high-level heat (HH) treatment could improve tenderness.

Potential mechanism of probiotic fermentation of var. Li./blueberry to reduce obesity induced by a high-fat diet.

The primary objective of this research was to investigate the effects of fermented var. Li/blueberry (FACB) on the gut microbiota of these super-large mouse models. The study, found that the groups who were given different amounts of FACB saw a significant reduction in their triglyceride and total cholesterol levels.

Preparation of Phosphorylated var. Li. Polysaccharide Liposome Gel and Analysis of Its In Vitro Antioxidant Activity.

In this study, var. Li. polysaccharides (ACP) were used as the research object to prepare liposome gel and determine its antioxidant activity in vitro.

Construction of clinical research nurse training program based on position competence.

Background: As one of the most important members in clinical trials, the number of clinical research nurses (CRN) can't keep up with the growth of experimental projects, so it is urgent to build clinical research training and strengthen the background knowledge of nurses.

Aim: To construct CRN training program based on position competence, accelerate the construction of CRN talent pool, and provide scientific guidance significance for CRN training.

Methods: Based on the position competence model, combined with literature research and qualitative interview results, the first draft was prepared of the CRN training program.

Influence of Polysaccharide Coating on the Stability and Antioxidant Activity of Liposomes Ginsenoside Rh2.

Liposomes (Lip) are microstructures containing lipid and aqueous phases for encapsulation and delivery of bioactivators. In this study, Ginsenoside Rh2 liposomes (Rh2-Lip) were prepared by a thin-film hydrated ultrasonic binding method. But they are not stable during storage.

Synchronous fluorescence detection of nitrite in meat products based on dual-emitting dye@MOF and its portable hydrogel test kit.

A novel ratiometric fluorescent nanoprobe (Rh6G@UIO-66-NH) was fabricated for efficient nitrite (NO) detection in the present study. When NO was introduced, it interacted with the amino groups on the surface of Rh6G@UIO-66-NH, forming diazonium salts that led to the quenching of blue fluorescence. With this strategy, a good linear relationship between NO concentration and the fluorescent intensity ratio of the nanoprobe in the range of 1-100 μM was established, with a detection limit of 0.

Study of the flavor dissipation mechanism of soy-sauce-marinated beef using flavor matrices.

Soy sauce-based marinade beef (SSMB) is a traditional Chinese cuisine with a unique flavor. However, pre-precooling and air-cooling tunnels are necessary industrial units in the cold chain for flavor dissipation. Sensory-directed flavor analysis was performed to identify the key aroma-active compounds in SSMB that had just completed (100 ℃), pre-cooled in the brine tanks (45 ℃), and exited the air-cooleded tunnel (10 ℃).

Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo.

Ethnopharmacological Relevance: Cynanchum komarovii (CK), the northwest Chinese region's common medicinal herb, was traditionally utilized to treat arthritis, toothache, bald sores and cholecystitis. Various forms of arthritis can be treated with CK, based on "Medicinal Plants of Chinese Desert Areas". However, the exact mechanism of action in rheumatoid arthritis (RA) is uncertain.

Targeting PHB1 to inhibit castration-resistant prostate cancer progression in vitro and in vivo.

Background: Castration-resistant prostate cancer (CRPC) is currently the main challenge for prostate cancer (PCa) treatment, and there is an urgent need to find novel therapeutic targets and drugs. Prohibitin (PHB1) is a multifunctional chaperone/scaffold protein that is upregulated in various cancers and plays a pro-cancer role. FL3 is a synthetic flavagline drug that inhibits cancer cell proliferation by targeting PHB1.

Structural characterization of polysaccharides after fermentation from and its antioxidant activity in HepG2 cells induced by HO.

In this study, ATCC14917 was used to ferment spore powder. Two polysaccharides were purified from unfermented (GLP) and fermented (FGLP) spore powder. The chemical structure and antioxidant activity of the polysaccharides were studied.

The properties and formation mechanism of ovalbumin-fucoidan complex.

The polymeric materials formed by proteins and polysaccharides through molecular interactions have attracted public attention. In this study, a novel binary complex consisting of ovalbumin (OVA) and fucoidan (FUC) was obtained by electrostatic self-assembly. The self-assembly properties and the formation mechanism of the OVA-FUC binary complex were investigated by changing the charging degree and density of complex through altering pH value and polysaccharides proportion.

Effect of the changs of microbial community on flavor components of traditional soybean paste during storage period.

Soybean paste is a tradition of fermented soybean paste products under natural conditions. This study used high-throughput sequencing and headspace-solid phase microextraction combined with gas chromatography-mass spectrometry to determine soybean paste's microbial communities and volatile components at different storage periods. Data analysis determined the key flora and their effects on flavor substances.

Recent Advances in Woven Spacer Fabric Sandwich Composite Panels: A Review.

Because of the advantageous characteristics of strong integrity, lightweight, high performance, and various designs, woven spacer fabric (WSF) and its composite are extensively used in construction, traffic, and aerospace, among other fields. This paper first describes the WSF structure, including core yarns and cross-linking, and then discusses the influence of the processing parameters, among angle of the wall decisive the failure mode on the plate properties. Moreover, we summarize the molding and filling technology of WSF composite sandwich panels and discuss the process order, resulting in a significant effect on the stiffness of the sandwich composite plate; the current processing is mostly hand lay-up technology.

Fungal Diversity in Barley Under Different Storage Conditions.

The diversity of fungi in barley in simulated storage environments was analyzed. Barley was stored at different temperatures (15, 25, 35°C) and relative humidity (55, 65, 75, 85 RH) for 180 and 360 days. Alpha diversity, beta diversity, species composition, and species differences were analyzed using Illumina HiSeq technology.

Structure identification of walnut peptides and evaluation of cellular antioxidant activity.

Walnut peptides are widely accepted as nutraceuticals with multiple health benefits. However, information about the structure and biological activity of walnut peptides is limited. In this work, walnut protein hydrolysate (WPH) was prepared by enzymatic hydrolysis.

PPFIA4 promotes castration-resistant prostate cancer by enhancing mitochondrial metabolism through MTHFD2.

Background: The development of castration-resistant prostate cancer (CRPC) remains a major obstacle in the treatment of prostate cancer (PCa). Dysregulated mitochondrial function has been linked to the initiation and progression of diverse human cancers. Deciphering the novel molecular mechanisms underlying mitochondrial function may provide important insights for developing novel therapeutics for CRPC.

Regulatory Mechanism of the Constitutive Photomorphogenesis 9 Signalosome Complex in Response to Abiotic Stress in Plants.

The constitutive photomorphogenesis 9 (COP9) signalosome (CSN) is a highly conserved protein complex that regulates signaling pathways in plants under abiotic stress. We discuss the potential molecular mechanisms of CSN under abiotic stress, including oxidative stress with reactive oxygen species signaling, salt stress with jasmonic acid, gibberellic acid, and abscisic acid signaling, high-temperature stress with auxin signaling, and optical radiation with DNA damage and repair response. We conclude that CSN likely participates in affecting antioxidant biosynthesis and hormone signaling by targeting receptors, kinases, and transcription factors in response to abiotic stress, which potentially provides valuable information for engineering stress-tolerant crops.