Publications by authors named "Junlan Yu"
Article Synopsis
- Phenol is highly toxic to aquatic life and accumulates in the environment, posing challenges for assessing ecological risks.
- A new three-stage assessment method revealed that phenol concentrations are generally higher in northern rivers of China, with ecological risks varying by season and river location.
- Fish are more vulnerable to phenol toxicity than invertebrates, highlighting the need for updated water quality standards and targeted strategies to protect river ecosystems.
The value of ecosystem services is affected by increasing human activities. However, the anthropogenic driving mechanisms of ecosystem services are poorly understood. Here, we established a deep learning model to approximate the ecosystem service value (ESV) of Nanjing City using 23 socioeconomic factors.
View Article and Find Full Text PDFAim: Fragment-based lead discovery (FBLD) is a complementary approach in drug research and development. In this study, we established an NMR-based FBLD platform that was used to screen novel scaffolds targeting human bromodomain of BRD4, and investigated the binding interactions between hit compounds and the target protein.
Methods: 1D NMR techniques were primarily used to generate the fragment library and to screen compounds.