PM2.5 potentiates oxygen glucose deprivation-induced neurovascular unit damage via inhibition of the Akt/β-catenin pathway and autophagy dysregulation.

Air pollution has recently emerged as a significant risk factor for ischemic stroke. Although there is a robust association between higher concentrations of ambient particulate matter (PM2.5) and increased incidence and mortality rates of ischemic stroke, the precise mechanisms underlying PM2.