Publications by authors named "Junkun Ren"

Article Synopsis
  • Higher coffee consumption may be linked to a lower risk of aggressive prostate cancer, potentially through effects on the PI3K signaling pathway involved in cancer development.
  • This study examined the relationship between prediagnostic coffee intake and various tumor markers in men with prostate cancer from a large cohort known as the Health Professionals Follow-Up Study.
  • Results indicated that while most participants were coffee drinkers, the overall associations between coffee intake and tumor markers were weak, with only minimal differences observed in PI3K activation scores and angiogenesis markers depending on coffee consumption levels.
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Objective: This exploratory study examined whether central auditory tests show differences between people living with HIV (PLWH) treated with two predominant antiretroviral drug therapy (ART) regimens.

Design: Cross-sectional.

Study Sample: 253 PLWH (mean age 39.

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Background: A unique syndrome affecting young adults of unexplained hearing loss often associated with uncorrectable poor visual acuity and lower extremity numbness is endemic in Dar es Salaam. This study characterized the hearing loss, associated it with other symptoms, and gathered information on potential causes.

Methods: Forty-seven patients (23 men, 24 women) <40 years old with a symptom consistent with the syndrome, negative syphilis test, and no head injury history were recruited from Muhimbili National Hospital.

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Urinary calcium (Uca) levels in space reflect bone loss and kidney stone risk and could be measured using portable devices. This project evaluated the repeatability of Uca measurements to assess how many repeated measurements would be needed to detect significant urinary calcium elevations in space. A total of six subjects collected 24-h urine samples weekly for 8 wk and took 500 mg of oral calcium carbonate and 400 IU of vitamin D daily in week 7 and 8.

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Anthocyanins as antioxidants are potential to protect liver from alcoholic damage, but might be pro-oxidants under certain conditions. In this study, twelve purple sweet potatoes anthocyanins (PSPA) were isolated and their effects on alcohol-induced liver injury were studied. These PSPA were rich in cyanidin derivatives and fed to male C57BL/6 mice as colorants in alcoholic drink with low, median, or high dosages PSPA i.

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