Publications by authors named "Junko Komori"
Isolates of extended-spectrum cephalosporin (ESC)-resistant Salmonella enterica serovar Typhimurium obtained from two different farms in Fukushima Prefecture, Japan, in 2007 were characterized in order to determine the genetic basis of resistance. ESC resistance in the two isolates was mediated by an AmpC β-lactamase encoded by the bla(CMY-2) gene, which is located in a large self-transmissible plasmid in each isolate. The sizes of the bla(CMY-2)-carrying plasmids were different.
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- Staphylococcus aureus (SA) is commonly found in skin lesions of atopic dermatitis (AD) and contributes to the disease's progression by releasing toxins that activate skin cells and increase levels of IL-18, leading to inflammation.
- Research shows a significant correlation between SA colony counts on the skin and IL-18 levels, linking these factors to the severity of AD in both human patients and DS-Nh mice, which serve as a model for studying the disease.
- CD25 +CD4 + regulatory T cells are identified as potentially key players in reducing AD symptoms by suppressing Th1 cell responses induced by IL-18, indicating a new avenue for AD treatment, particularly in the context of treatments affecting immune regulation.