Publications by authors named "Junko Fukuchi"
Article Synopsis
- - This study examines the effects of repetitive transcranial magnetic stimulation (rTMS) on patients with treatment-resistant depression (TRD), focusing on the role of soluble TREM2, a protein linked to inflammation and microglial activity.
- - Results showed that rTMS improved depressive symptoms and cognitive function in the participants, but did not change serum levels of sTREM2, suggesting it may not play a role in rTMS's therapeutic effects.
- - The authors recommend further research with larger samples and different methods to better understand the relationship between rTMS and sTREM2 in depression treatment.
Background: Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation technique that is considered a valuable and promising technique for improving depressive symptoms in treatment-resistant depression (TRD). However, the exact mechanism by which rTMS ameliorates depressive symptoms remains to be clarified.
Objective: The aim of the present study was to analyzed the changes in metabolites of patients with TRD in the rTMS treatment, especially focusing on the kynurenine (KYN) pathway.
We have cloned the rpoZ gene, encoding RNA polymerase omega protein, by PCR approach from the deep-sea piezophilic and psychrophilic bacterium, Shewanella violacea strain DSS12. The cloned gene, 285bp in length, was found to encode a protein consisting of 94 amino acid residues with a molecular mass of 10,327 Da. Significant homology was evident comparing the RpoZ protein of S.
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