Post-pericardiectomy ECMO for constrictive pericarditis: a case series and literature review.

Background: Pericardiectomy is the curative treatment for constrictive pericarditis, yet postoperative low cardiac output syndrome (LCOS) may occur. The application of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in post-pericardiectomy refractory LCOS has limited case reports, and its effectiveness and safety remain unclear. This study aims to provide evidence for the effectiveness of ECMO in treating post-pericardiectomy refractory LCOS.

Square-shaped CuMoS loaded on three-dimensional flower-like AgBiS to form S-scheme heterojunction as a light-driven photoelectrochemical sensor for efficient detection of serotonin in biological samples.

Serotonin (5-HT) is a crucial neurotransmitter in the body, with its levels being particularly significant for life safety. Here, we designed the AgBiS/CuMoS S-scheme heterojunction by uniformly immobilizing lamellar CuMoS on the surface of three-dimensional (3D) flower-like AgBiS using a simple physical mixing technique. In this case, AgBiS and CuMoS are bonded together by electrostatic attraction to form an active surface with a large specific surface area.

pSTAT3 transactivates EGFR in maintaining EGFR protein homeostasis and EGFR-TKI resistance.

EGFR protein trafficking is critical for regulating multiple biological processes, including cell growth and survival. However, how EGFR protein homeostasis is maintained remains unclear. In this study, we show that a reduction in plasma membrane-associated EGFR triggers EGFR transcription by promoting pSTAT3 nuclear localization.

Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation.

Glucose deprivation, a hallmark of the tumor microenvironment, compels tumor cells to seek alternative energy sources for survival and growth. Here, we show that glucose deprivation upregulates the expression of mitochondrial-cytochrome c oxidase II (MT-CO2), a subunit essential for the respiratory chain complex IV, in facilitating glutaminolysis and sustaining tumor cell survival. Mechanistically, glucose deprivation activates Ras signaling to enhance MT-CO2 transcription and inhibits IGF2BP3, an RNA-binding protein, to stabilize MT-CO2 mRNA.

Ultrafine metal-organic framework @ graphitic carbon with MoS-CNTs nanocomposites as carbon-based electrochemical sensor for ultrasensitive detection of catechin in beverages.

GO/Co-MOF/PPy-350 (GPC-350) was synthesized by in situ growth of ultrafine Co-MOF on graphene oxide (GO), followed by encapsulation with polypyrrole (PPy) and calcination at 350.0℃. Meanwhile, MoS-MWCNTs (MoS-CNTs) were produced via the in situ synthesis of MoS within multi-walled carbon nanotubes (MWCNTs).

A review on Pd-M bimetallic electrochemical sensors: Techniques, performance, and applications.

Environmental pollution, food safety, and medical diagnostics pose severe threats to human health, making the development of effective detection technologies crucial. Electrochemical sensors, as an efficient detection method, are extensively employed in detecting environmental pollutants, food additives, and biomolecules. Pd-M bimetallic materials, known for their excellent electrocatalytic performance, are extensively utilized as electrode modification materials.

Bimetallic PdCu anchored to 3D flower-like carbon material for portable and efficient detection of glyphosate.

Glyphosate (Gly), as a widely used broad-spectrum herbicide, may lead to soil and water pollution due to its persistence in the environment. Herein, the co-reduction method was employed to anchor bimetallic PdCu onto the Ni and nitrogen-doped 3D Flower-like Carbon Materials (Ni@NC), creating a composite material (PdCu/Ni@NC) with high specific surface area and good catalytic performance. This composite was used to modify screen-printed electrodes (SPE) to develop a portable and efficient Gly detection platform.

2D/3D hierarchical porous structure of mNPC/SMOH@C to construct an electrochemical sensor for the simultaneous determination of p-acetylaminophenol and p-aminophenol.

Background: As persistent organic pollutants (POPs), the accumulation of p-acetylaminophenol (PAT) and p-aminophenol (PAP) in water can seriously damage the health of plants and animals, ultimately leading to threats to human health and safety. Electrochemical sensors have the advantages of being fast, inexpensive, and accurate compared to the complex, expensive, and cumbersome conventional analytical methods. In this study, we designed and synthesized composites with two-dimensional/three-dimensional (2D/3D) porous structures to construct an efficient electrochemical platform for the simultaneous detection of PAT and PAP.

A novel electrochemical sensor for detection of luteolin in food based on 3D networked electrically interconnected SiO@GO/MXene composite.

Luteolin (Lu), a compound with various biochemical and pharmacological activities beneficial to human health, has attracted researchers' attention. This study proposes an efficient and scalable method using ultrasound to intercalate graphene oxide (GO)-coated silica spheres (SiO) into MXenes, resulting in a 3D conductive interconnected structural composite material. Characterization of the composite material was conducted using SEM, TEM, XRD, XPS, and Raman spectroscopy.

Electrochemical sensing platform using reduced graphene oxide and Sn MOF-derived hollow cubic composites for sensitive detection of catechol in environmental water samples.

Catechol, a polyphenolic molecule and significant organic chemical intermediate, is a highly dangerous environmental contaminant due to its unpredictable nature and potential harm to both humans and the environment. This study presents the development of Sn MOF@rGO-650, identified as a hollow cube by SEM and TEM, created by carbonizing rGO on the surface of Sn MOF after in situ encapsulation. The Sn MOF@rGO-650 modified glassy carbon electrode was successfully constructed for the electrochemical detection of catechol.

Ultra-sensitive electrochemical sensor based on in situ grown ultrafine HKUST-1 nanoparticles @ graphite nanosheets and core-shell structured MoO-polypyrrole nanowires for the detection of rutin in orange juice.

Rutin extracted from natural plants has important medical value, so developing accurate and sensitive quantitative detection methods is one of the most important tasks. In this work, HKUST-1@GN/MoO-Ppy NWs were utilized to develop a high-performance rutin electrochemical sensor in virtue of its high conductivity and electrocatalytic activity. The morphology, crystal structure, and chemical element composition of the fabricated sensor composites were characterized by SEM, TEM, XPS, and XRD.

In-situ synthesized MgInS/CdWO type-II heterojunction as a light-driven photoelectrochemical sensor for ultrasensitive detection of catechol in environmental water samples.

As an essential chemical intermediate, catechol (CC) residues may have adverse effects on human health. Herein, an effective and facile photoelectrochemical sensor platform based on MgInS/CdWO composite is constructed for monitoring CC. MgInS increases light absorption range and activity, while CdWO enhances photoelectronic stability, and the type-II heterojunction formed can significantly enhance photocurrent response.

Multilayer TiC-CNTs-Au Loaded with Cyclodextrin-MOF for Enhanced Selective Detection of Rutin.

In this work, multi-layer TiC - carbon nanotubes - gold nanoparticles (TiC-CNTs-Au) and cyclodextrin metal-organic framework - carbon nanotubes (CD-MOF-CNTs) have been prepared by in situ growth method and used to construct the ultra-sensitive rutin electrochemical sensor for the first time. Among them, the large number of metal active sites of TiC, the high electron transfer efficiency of CNTS, and the good catalytic properties of AuNPs significantly enhance the electrochemical properties of the composite carbon nanomaterials. Interestingly, CD-MOF has a unique host-guest recognition and a large number of cavities, molecular gaps, and surface reactive groups, which gives the composite outstanding accumulation properties and selectivity for rutin.

USP36 stabilizes nucleolar Snail1 to promote ribosome biogenesis and cancer cell survival upon ribotoxic stress.

Tumor growth requires elevated ribosome biogenesis. Targeting ribosomes is an important strategy for cancer therapy. The ribosome inhibitor, homoharringtonine (HHT), is used for the clinical treatment of leukemia, yet it is ineffective for the treatment of solid tumors, the reasons for which remain unclear.

Detection of luteolin in food using a novel electrochemical sensor based on cobalt-doped microporous/mesoporous carbon encapsulated peanut-like FeO composite.

Luteolin (Lu) is a dietary flavonoid that has attracted much attention due to its multiple health benefis effects. Herein, an ultrasensitive electrochemical sensor for Lu was constracted based on cobalt-doped microporous/mesoporous carbon (MMC) encapsulated peanut-like FeO composite. The FeOx-Co-MMC composite was obtained by pyrolyzing a precursor named FeO-Co-microporous/mesoporous dopamine (FeO-Co-MMPDA) which was synthesized by a soft template method.

Detection of gallic acid in food using an ultra-sensitive electrochemical sensor based on glass carbon electrode modified by bimetal doped carbon nanopolyhedras.

Gallic acid is widely used as an antioxidant in food because of its good antioxidant function, but excessive intake induces side effects in humans, so it is essential to devise a highly responsive technique for detecting gallic acid. In this work, we synthesized ZIF-67@FePc by the one-pot method. The synthesized material is more stable at high temperatures compared to ZIF-67 and maintains its original morphology during pyrolysis, when iron was introduced as a second metal active site during the synthesis process.

Fabricating process-electrochemical property correlation of laser-scribed graphene and smartphone-based electrochemical platform for portable and sensitive biosensing.

Laser-scribed graphene (LSG), a promising electrode material has attracted special research interest in recent years. Here, the fabricating process-electrochemical property correlation of laser-scribed graphene (LSG) devices was discussed emphatically and a pertinent optimization was performed to achieve better electroanalytical performance. Experiment results indicated that the laser scribing technique possessed great process latitude and reducing laser power and scribing speed facilitated fabricating high-quality graphene electrodes.

Electrochemical Behavior of β-Cyclodextrin-Ni-MOF-74/Reduced Graphene Oxide Sensors for the Ultrasensitive Detection of Rutin.

Rutin, as a biological flavonoid glycoside, has very important medicinal value. The accurate and rapid detection of rutin is of great significance. Herein, an ultrasensitive electrochemical rutin sensor based on β-cyclodextrin metal-organic framework/reduced graphene oxide (β-CD-Ni-MOF-74/rGO) was constructed.

An ultrasensitive dietary caffeic acid electrochemical sensor based on Pd-Ru bimetal catalyst doped nano sponge-like carbon.

Caffeic acid (CA) is widely present in the human daily diet, and a reliable CA detection method is beneficial to food safety. Herein, we constructed a CA electrochemical sensor employing a glassy carbon electrode (GCE) which was modified by the bimetallic Pd-Ru nanoparticles decorated N-doped spongy porous carbon obtained by pyrolysis of the energetic metal-organic framework (MET). The high-energy bond N-NN in MET explodes to form N-doped sponge-like carbon materials (N-SCs) with porous structures, boosting the adsorptive capacity for CA.

An electrochemical sensor based on Ce-MOF-derived Ce-doped poly(3,4-ethylenedioxythiophene) composite for efficient determination of rutin in food.

As a common antioxidant and nutritional fortifier in food chemistry, rutin has positive therapeutic effects against novel coronaviruses. Here, Ce-doped poly(3,4-ethylenedioxythiophene) (Ce-PEDOT) nanocomposites derived through cerium-based metal-organic framework (Ce-MOF) as a sacrificial template have been synthesized and successfully applied to electrochemical sensors. Due to the outstanding electrical conductivity of PEDOT and the high catalytic activity of Ce, the nanocomposites were used for the detection of rutin.

A light-driven photoelectrochemical sensor for highly selective detection of hydroquinone based on type-II heterojunction formed by carbon nanotubes immobilized in 3D honeycomb CdS/SnS.

The ecological environment and public safety are seriously threatened by the typical phenolic contaminant hydroquinone (HQ). Here, using a straightforward physical mixing technique, we created an n-n heterojunction by uniformly immobilizing cadmium sulfide (CdS) nanoparticles on the surface of a three-dimensionally layered, flower-like structure made of tin sulfide (SnS). Then, as photosensitizers, carbon nanotubes (CNTs) were added to the CdS/SnS complex to create a type-II heterostructure of CdS/SnS/CNTs with synergistic effects.

A "Special" Solvent to Prepare Alloyed PdNi Nanoclusters on a MWCNT Catalyst for Enhanced Electrocatalytic Oxidation of Formic Acid.

Herein, an electrocatalyst with PdNi nanoclusters, supporting multiwalled carbon nanotubes (MWCNTs) (referred to PdNi/CNTs), was fabricated with deep eutectic solvents (DES), which simultaneously served as reducing agent, dispersant, and solvent. The mass activity of the catalyst for formic acid oxidation reaction (FAOR) was increased nearly four times compared to a Pd/C catalyst. The excellent catalytic activity of PdNi/CNTs was ascribed to the special nanocluster structure and appropriate Ni doping, which changed the electron configuration of Pd to reduce the d-band and to produce a Pd-Ni bond as a new active sites.

HSF1 activates the FOXO3a-ΔNp63α-CDK4 axis to promote head and neck squamous cell carcinoma cell proliferation and tumour growth.

Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent cancers worldwide. Heat shock factor 1 (HSF1) is a conserved transcriptional factor that plays a critical role in maintaining cellular proteostasis. However, the role of HSF1 in HNSCC development remains largely unclear.

Neuromorphic functions with a polyelectrolyte-confined fluidic memristor.

Reproducing ion channel-based neural functions with artificial fluidic systems has long been an aspirational goal for both neuromorphic computing and biomedical applications. In this study, neuromorphic functions were successfully accomplished with a polyelectrolyte-confined fluidic memristor (PFM), in which confined polyelectrolyte-ion interactions contributed to hysteretic ion transport, resulting in ion memory effects. Various electric pulse patterns were emulated by PFM with ultralow energy consumption.

A novel photoelectrochemical sensor based on flower-like SnS, sea urchin-like AgBiS and graphene oxide nanocomposite film for efficient and sensitive detection of acetaminophen in lake water samples.

As an emerging detection technology, photoelectrochemical sensors have been widely noticed for their unique technical features. Among others, the technology has been widely used in the fields of drug, biological antibody or antigen and contaminant detection. Secondly, acetaminophen, as a novel environmental pollutant, is difficult to be degraded in the ecosystem, which in turn causes serious impacts on the ecosystem.