Synopsis of recent research by authors named "Junji Zhu"
- Junji Zhu's recent research primarily focuses on the role of posttranslational modifications, particularly ISGylation and ubiquitination, in the regulation of antiviral immune responses, highlighting their significance in controlling viral replication and pathogenesis.
- His findings reveal that ISGylation of viral and host proteins, such as the MDA5 and SARS-CoV-2 N protein, plays a crucial role in facilitating immune signaling and preventing viral replication, indicating potential targets for therapeutic intervention.
- Additionally, Zhu's work underscores the importance of cellular factors, such as ADAM9 and various methyltransferases, in modulating type I interferon signaling and overall antiviral immunity, shedding light on complex host-pathogen interactions.