Comparison of the systemic action of electroacupuncture and laserpuncture in experimental injuries on the back skin of Wistar rats (Rattus novergicus).

Objective: To evaluate the systemic action of electroacupuncture and laserpuncture in the repair of excisional cutaneous injuries on the back of adult female Wistar rats.

Methods: Ninety animals were divided into three experimental groups: C-control; E-treated with electroacupuncture [acupoints: Feishu (BL13), Geshu (BL17), Zusanli (ST36)]; L-treated with laserpuncture (same acupoints) and euthanized on the 7th, 14th and 21st days for tissue removal and preparation for histomorphometric and biochemical (dosages, zymography and Western blotting) analysis.

Results: The number of fibroblasts in the E and L groups presented higher values than the C on the 14th and 21st days.

Engineered 3D printed poly(ɛ-caprolactone)/graphene scaffolds for bone tissue engineering.

Scaffolds are important physical substrates for cell attachment, proliferation and differentiation. Multiple factors could influence the optimal design of scaffolds for a specific tissue, such as the geometry, the materials used to modulate cell proliferation and differentiation, its biodegradability and biocompatibility. The optimal design of a scaffold for a specific tissue strongly depends on both materials and manufacturing processes.