Publications by authors named "Junichiro Hagita"
Background: Metformin-induced lactic acidosis with acute kidney injury is rare but well known. Here we report a case of a Japanese patient taking metformin who experienced severe acute renal failure accompanied with significantly elevated metformin plasma concentrations and signs of lactic acidosis.
Case Presentation: A 60-year-old Japanese man with type II diabetes, who was taking metformin (500 mg three times a day) along with several other medications, visited the emergency department with dizziness, malaise, and oliguria.
Article Synopsis
- - Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare type of vasculitis that mainly affects small to medium blood vessels and is often linked to eosinophil-related inflammation, impacting systems like the lungs and nervous system but rarely causing limb ulcers.
- - An 86-year-old Japanese woman with anti-neutrophil cytoplasmic antibody-negative EGPA experienced sudden ulcers in her upper limbs and foot drop due to nerve issues, which were confirmed through a nerve biopsy showing eosinophil damage.
- - Treatment with steroids, intravenous immunoglobulin, vasodilators, and mepolizumab led to significant improvement in her ulcers and nerve function, suggesting that early use of
Background And Aims: End-stage renal disease is associated with an increased risk of atherosclerotic vascular disease (AVD). We investigated whether low plantar skin perfusion pressure (SPP), a useful indicator of peripheral arterial disease (PAD), predicts systemic AVD events and mortality in outpatients undergoing maintenance haemodialysis (HD).
Methods: A total of 206 HD patients were enrolled and followed for 5 years.