Publications by authors named "Junia Marielle Teixeira Rodrigues Neri"
Synbiotic Supplementation Modulates Gut Microbiota, Regulates β-Catenin Expression and Prevents Weight Gain in ob/ob Mice: Preliminary Findings.
Sebastião Mauro B Duarte José Tadeu Stefano Lucas A M Franco Roberta C Martins Bruna D G C Moraes Junia Marielle Teixeira Rodrigues Neri
Int J Mol Sci
September 2022
Article Synopsis
- Obesity is a major global health issue, and this study explores the effects of synbiotic supplementation on obesity and gut microbiota in ob/ob mice, divided into four groups for comparison.
- After 8 weeks of treatment, synbiotic supplementation in obese mice led to reduced weight gain and changes in gut bacteria composition, specifically an increase in Enterobacteriaceae and a decrease in Cyanobacteria.
- The findings also indicated a significant reduction in β-Catenin gene expression in the treated obese group, suggesting that synbiotics may help manage obesity by influencing gut health and microbiota.
Background: Incisional hernias are more frequent in adults than in children. It is hypothesized that a more efficient healing process in pediatric patients could explain this difference in incidence. Certain elements of healing such as neovascularization, degree of inflammation, percentage of mature and immature collagen, the proliferation of fibroblasts, and expression of certain genes could explain why healing in children is more efficient when compared to the adult and elderly populations.
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