Publications by authors named "Junhyung Bae"
Article Synopsis
- A study investigated the changing patterns of paranasal sinus fungus balls, which are increasingly common in rhinosinusitis cases.
- Researchers analyzed data from 35 of 41,497 patients who had brain MRIs, grading the severity of the fungus balls and examining how their progression was affected by various factors.
- Results indicated that fungus balls showed significant changes over time, with a marked difference in the interval between initial and final MRI scans, while other factors like age and dental history showed no significant impact on progression.
Purpose: The poor response of breast cancer to immune checkpoint blockade might result from low immunogenicity and the immune-suppressive tumor microenvironment. We hypothesized that in situ tumor vaccination via radiation therapy (RT) and suppression of immune tolerance via phosphoinositide 3-kinase δ (PI3Kδ) inhibition would enhance the efficacy of immune checkpoint blockade.
Methods And Materials: 4T1 murine breast cancer cells were grown in both immune-competent and -deficient BALB/c mice, and tumors were irradiated with 24 Gy in 3 fractions.