A calcium channel blocker, manoalide exerts an anti-allergic inflammatory effect through attenuating NF-κB activity.

Background: Many people are troubled by allergic inflammation including ocular allergic diseases, anaphylaxis, allergic rhinitis, atopic dermatitis, and eczema. Consequently, finding medications for use in allergic inflammation therapy is crucial in human health. Manoalide, a marine natural product isolated as an anti-bacterial metabolite from , is a calcium channel blocker.

Developing Growth-Associated Molecular Markers Via High-Throughput Phenotyping in Spinach.

High-throughput imaging and genomic information can be combined to optimize marker development. Genome-wide association studies identified loci associated with plant growth traits. We identified candidate genes associated with plant growth and development.

The ameliorative effect of AST2017-01 in an ovalbumin-induced allergic rhinitis animal model.

Objective: AST2017-01 is developed to be used for treatment and prevention of allergic diseases and composed of processed-Cordyceps militaris and processed-Rumex crispus. But, effect of AST2017-01 remains unclear in an allergic rhinitis (AR). So, this study aimed to explore the effects of AST2017-01 in ovalbumin (OVA)-induced AR animal model.