Achieving a Balance of Good Quantum Efficiency and Thermal Stability in the YCaScAlGeO:Cr Broadband Phosphor for Multiple NIR Spectroscopy Applications.

Near-infrared phosphor-converted light emitting diodes (NIR pc-LEDs) are considered as desirable NIR light sources to satisfy current needs owing to their numerous remarkable features. Nevertheless, as an essential component, previously reported NIR phosphors with broadband emission often suffer from inferior efficiency or thermal stability, therefore restricting their use and promotion. Herein, a novel Cr-doped garnet phosphor YCaScAlGeO:Cr (YCSAG:Cr) is developed via regulating the near-neighbor coordination polyhedron.

Acetyllevocarnitine Hydrochloride for the Treatment of Diabetic Peripheral Neuropathy: A Phase 3 Randomized Clinical Trial in China.

Diabetic peripheral neuropathy (DPN) is a highly prevalent chronic complication in type 2 diabetes (T2D) for which no effective treatment is available. In this multicenter, randomized, double-blind, placebo-controlled phase 3 clinical trial in China, patients with T2D with DPN received acetyllevocarnitine hydrochloride (ALC; 1,500 mg/day; n = 231) or placebo (n = 227) for 24 weeks, during which antidiabetic therapy was maintained. A significantly greater reduction in modified Toronto clinical neuropathy score (mTCNS) as the primary end point occurred in the ALC group (-6.

An efficient and thermally stable Cr-activated YGdScAlGaO garnet phosphor for NIR spectroscopy applications.

Near-infrared (NIR) spectroscopy realized by an NIR phosphor-converted light-emitting diode (pc-LED) as a light source has aroused considerable interest due to its numerous merits and widespread application scenarios. Nevertheless, developing NIR emitting phosphors with high performance is still the top priority. Here, we report a new YGdScAlGaO:Cr (YGSAG:Cr) garnet phosphor, which demonstrates a broadband emission peaking at 754 nm with a full width at half maximum (FWHM) of around 120 nm in the range of 650-1200 nm.

A randomized, double-blind, placebo controlled, phase 3 trial to evaluate the efficacy and safety of cetagliptin added to ongoing metformin therapy in patients with uncontrolled type 2 diabetes with metformin monotherapy.

Aim: This trial was designed to assess the efficacy and safety of cetagliptin added to metformin in Chinese patients with type 2 diabetes who had inadequate glycaemic control with metformin monotherapy.

Methods: In total, 446 patients with type 2 diabetes on metformin monotherapy were randomized to receive the addition of once-daily cetagliptin 100 mg, cetagliptin 50 mg and placebo in a 2:2:1 ratio for 24-week double-blind treatment. At week 24, patients initially randomized to cetagliptin 50 mg and placebo were switched to cetagliptin 100 mg for 28 weeks open-label treatment.

Near-Infrared LuCaScZrGaGeO:Cr Garnet Phosphor with Ultra-broadband Emission for NIR LED Applications.

Near-infrared phosphor-converted light-emitting diodes (NIR pc-LEDs), as a new generation of NIR lighting sources, have wide prospects in the areas of food analysis and biological and night vision imaging. Nevertheless, NIR phosphors are still limited by short-wave and narrowband emissions as well as low efficiency. Herein, a series of NIR phosphors, LuCaScZrGaGeO:Cr (LCSZGG:Cr), with broadband emissions have been developed and first reported.

Multisite Cation Regulation of Broadband Cyan-Emitting (BaSr)LuSiO/Eu Phosphors for Full-Spectrum wLEDs.

Developing broadband cyan-emitting phosphors is an essential issue to achieve high-quality full-spectrum phosphor-converted white light-emitting diodes. Multisite cation regulation to modify the photoluminescence spectrum is a valid way to achieve broadband emission for phosphors. The BaLuSiO lattice with various cation sites for activator ions is a preferred host for broadband emitting phosphors.

Garnet phosphors for white-light-emitting diodes: modification and calculation.

Phosphor-converted white-light-emitting diodes (pc-wLEDs) have attracted considerable attention in general lighting and backlight display applications due to their high efficiency and long lifetime. The combination of Ce-doped yttrium aluminium garnet (YAG:Ce) with a blue LED chip is the most mature technology to obtain white light emission. Because of the excellent structural flexibility of garnet, many novel garnet phosphors have been designed and developed in the past few years.