pH-Sensitive Polyacrylic Acid-Gated Mesoporous Silica Nanocarrier Incorporated with Calcium Ions for Controlled Drug Release.

In this work, polyacrylic acid-functionalized MCM-41 was synthesized, which was made to interact with calcium ions, in order to realize enhanced pH-responsive nanocarriers for sustained drug release. First, mesoporous silica nanoparticles (MSNs) were prepared by the sol-gel method. Afterward, a (3-trimethoxysilyl)propyl methacrylate (TMSPM) modified surface was prepared by using the post-grafting method, and then the polymerization of the acrylic acid was performed.

Tunable multi-responsive nano-gated mesoporous silica nanoparticles as drug carriers.

Tunable multi-responsive mesoporous silica nanoparticles were prepared by post-condensation/surface modification of MCM-41 nanoparticles. Surface grafting of a poly(N,N-dimethylaminoethyl methacrylate)-based polymer containing disulfide bonds was achieved by a click reaction. Chemical modification, morphological characteristics, and textural properties of the nanoparticles were studied using multiple characterization techniques such as Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, small-angle X-ray scattering, and nitrogen adsorption/desorption behavior.

Functionalized Mesoporous Silica for Highly Selective Sensing of Iron Ion in Water.

In this study, we examined the highly selective sensing of Fe ions in water using metal complex-functionalized mesoporous silica materials. Metal complex-functionalized mesoporous silica materials were synthesized on the mesoporous surface of SBA-15 via complexation process between Eu and aminosilane groups. Mesoporous silica, SBA-15, and the Eu-complex functionalized SBA-15 were characterized using X-ray diffraction (XRD), transmittance electron microscopy (TEM), nitrogen sorption behavior, and Fourier transform infrared (FTIR) spectroscopy.