Non-specific uptake of F-FAPI-04 in the pancreas and its related factors: a post-hoc analysis of an ongoing prospective clinical trial.

This study aimed to analyze the characteristics of the non-specific uptake (NSU) of F-labeled fibroblast activation protein inhibitor (F-FAPI) of the pancreas and investigate the related factors. Totally, 78 patients who underwent both F-fluorodeoxyglucose (FDG) and F-FAPI PET/CT examinations were divided into normal (n = 53) and NSU (n = 25) groups. The differences in general information, medical history, laboratory indexes and uptake were compared.

Evaluating the value of F-PSMA-1007 PET/CT in the detection and identification of prostate cancer using histopathology as the standard.

Background: Prostate-specific membrane antigen (PSMA) PET/CT is a highly regarded radionuclide imaging modality for prostate cancer (PCa). This study aimed to evaluate the diagnostic performance of F-PSMA-1007 PET/CT in detecting intraprostatic lesions of PCa using radical prostatectomy (RP) specimens as a reference standard and to establish an optimal maximum standardized uptake value (SUVmax) cutoff for distinguishing between PCa and non-PCa lesions.

Methods: We retrospectively collected 117 patients who underwent F-PSMA-1007 PET/CT before RP.

The prognostic value of F-PSMA-1007 PET/CT in predicting pathological upgrading of newly diagnosed prostate cancer from systematic biopsy to radical prostatectomy.

Objective: This study aimed to evaluate predictors for upgrading of newly diagnosed prostate cancer from systematic biopsy (SB) to radical prostatectomy (RP) using fluorine-18 prostate-specific membrane antigen 1007 (F-PSMA-1007) positron emission tomography/computed tomography (PET/CT) and association with clinical parameters.

Materials And Methods: We retrospectively collected data from biopsy-confirmed prostate cancer (PCa) patients who underwent F-PSMA-1007 PET/CT prior to RP from July 2019 and October 2022. Imaging characteristics derived from F-PSMA-1007 PET/CT and clinical parameters were compared in patients of pathological upgrading and concordance subgroups.

Evaluation of a radiomics nomogram derived from Fluoride-18 PSMA-1007 PET/CT for risk stratification in newly diagnosed prostate cancer.

Objective: The aim of this study was to evaluate the performance of Fluoride-18 (F)-PSMA-1007-PET/CT radiomics for the tumor malignancy and clinical risk stratification in primary prostate cancer (PCa).

Materials And Methods: A total of 161 pathological proven PCa patients in a single center were retrospectively analyzed. Prostate-specific antigen (PSA), Gleason Score (GS) and PET/CT indexes (SUVmin, SUVmax, and SUVmean) were compared according to risk stratification.

The F-PSMA-1007 PET/CT performance on metastasis status and therapy assessment in oligo-metastasis prostate cancer.

Objective: The prostate-specific membrane antigen (PSMA) PET/CT is potentially identifying patients with oligo-metastasis who would be deemed to only have localized disease in the traditional approaches. However, the best selected oligo-metastasis prostate cancer (PCa) patients most likely to benefit from system androgen deprivation therapy (ADT) are still unknown. The aim of this study was to explore the potential F-PSMA-1007 PET/CT parameters and clinicopathologic characteristics for oligo-metastasis PCa discrimination and follow-up evaluation.

Cost-Effectiveness of Life Cycle Cost Theory-Based Large Medical Equipment.

The purpose of this study is to use the life cycle cost theory to analyze the efficiency of large medical equipment in hospitals, so as to implement life cycle cost (LCC) management and solve the current problems in hospitals. The analysis model of cost benefit of large medical equipment is established, and the cost-effectiveness of 4 large medical equipment between 2019 and 2021 is investigated and analyzed. In terms of the data in each information system of hospitals, the utilization of large medical equipment is quantitatively evaluated and analyzed by life cycle theory.

Evaluating environmental change and behavioral decision-making for sustainability policy using an agent-based model: A case study for the Smoky Hill River Watershed, Kansas.

Sustainability has been at the forefront of the environmental research agenda of the integrated anthroposphere, hydrosphere, and biosphere since the last century and will continue to be critically important for future environmental science. However, linking humans and the environment through effective policy remains a major challenge for sustainability research and practice. Here we address this gap using an agent-based model (ABM) for a coupled natural and human systems in the Smoky Hill River Watershed (SHRW), Kansas, USA.

Impaired brain glucose metabolism in cirrhosis without overt hepatic encephalopathy: a retrospective 18F-FDG PET/CT study.

Objectives: There are subclinical neurologic deficits in cirrhotic patients without overt hepatic encephalopathy. We aimed to use F-fluorodeoxyglucose PET/computed tomography to explore the impaired brain glucose metabolism of subclinical hepatic encephalopathy in cirrhosis.

Methods: Thirty-seven patients with hepatitis B virus-related cirrhosis without overt hepatic encephalopathy and 49 controls were enrolled in the study.

A quantitative evaluation of pleural effusion on computed tomography scans using B-spline and local clustering level set.

Estimation of the pleural effusion's volume is an important clinical issue. The existing methods cannot assess it accurately when there is large volume of liquid in the pleural cavity and/or the patient has some other disease (e.g.

SUVmax of 18F-FDG PET/CT correlates to expression of major chemotherapy-related tumor markers and serum tumor markers in gastric adenocarcinoma patients.

The expression of P53 was previously found by us significantly correlated with maximal standardized uptake value (SUVmax) in non-small cell lung cancer (NSCLC) patients. Hence, the aim of this study was to clarify the relationship between SUVmax and the status of the chemotherapy-related tumor marker expression or serum tumor markers in gastric adenocarcinoma patients. Sixty-four gastric adenocarcinoma patients who underwent 18F-FDG PET/CT prior to treatment were enrolled in this study.

Cytoxicity, dynamic and thermal properties of bio-based rosin-epoxy resin/ castor oil polyurethane/ carbon nanotubes bio-nanocomposites.

In order to prepare bio-nanocomposites with no-cytotoxicity, the rosin-based epoxy resin (MPAER) and castor oil-based polyurethane (COPU) were synthesized and carbon nanotubes (CNTs) was used to enhance the properties of curing MPAER/COPU materials. The curing reaction, dynamic mechanical and thermal properties of this system were characterized by FTIR, NMR, DMA, TG et al. The cytotoxicity of materials is evaluated for HeLa cells using a MTT cell-viability assay.

Fluorodeoxyglucose positron emission tomography and chemotherapy-related tumor marker expression in non-small cell lung cancer.

Background: The chemotherapy resistance of non-small cell lung cancer (NSCLC) remains a clinic challenge and is closely associated with several biomarkers including epidermal growth factor receptor (EGFR) ( Drugs 72(Suppl 1):28-36, 012.), p53 ( Med Sci Monit 11(6):HY11-HY20, 2005.) and excision repair cross complementing gene 1 (ERCC1) ( J Thorac Oncol 8(5):582-586, 2013.

Liquid crystalline phase behavior and sol-gel transition in aqueous halloysite nanotube dispersions.

The liquid crystalline phase behavior and sol-gel transition in halloysite nanotubes (HNTs) aqueous dispersions have been investigated by applying polarized optical microscopy (POM), macroscopic observation, rheometer, small-angle X-ray scattering, scanning electron microscopy, and transmission electron microscopy. The liquid crystalline phase starts to form at the HNT concentration of 1 wt %, and a full liquid crystalline phase forms at the HNT concentration of 25 wt % as observed by POM and macroscopic observation. Rheological measurements indicate a typical shear flow behavior for the HNT aqueous dispersions with concentrations above 20 wt % and further confirm that the sol-gel transition occurs at the HNT concentration of 37 wt %.

Preparation and characterization of bionanocomposite fiber based on cellulose and nano-SiO2 using ionic liquid.

Microcrystalline cellulose (MCC)/nano-SiO2 composite fibers were processed from solutions in 1-allyl-3-methylimidazolium chloride (AMIMCl) by the method of dry-jet wet spinning. The oscillatory shear measurements demonstrated that the gel network formed above 10 wt% nano-SiO2 and the complex viscosity increased with increasing nano-SiO2. Remarkably, the shear viscosity of the nanofluids was even lower than solutions without nano-SiO2 under high shear rates.

The preparation of 3,5-dihydroxy-4-isopropylstilbene nanoemulsion and in vitro release.

We have reported a novel procedure to prepare 3,5-dihydroxy-4-isopropylstilbene (DHPS) nanoemulsion, using a low-energy emulsification method. Based on the phase diagram, the optimum prescription of nanoemulsion preparation was screened. With polyoxyethylenated castor oil (EL-40) as the surfactant, ethanol as the co-surfactant, and isopropyl myristate (IPM) as the oil phase, the DHPS nanoemulsion was obtained with a transparent appearance, little viscosity, and spherically uniform distribution verified by transmission electron microscopy and laser scattering analyzer.

Curing kinetics of o-cresol formaldehyde epoxy resin and succinic anhydride system catalyzed by tertiary amine.

The kinetics of the cure reaction for system of o-cresol formaldehyde epoxy resin (o-CFER)/succinic anhydride (SA) and tertiary amine as a catalyst was investigated with a differential scanning calorimeter (DSC). Autocatalytic behavior was shown in the first stages of the cure for the system, which was well described by the model proposed by Kamal that includes two rate constants, k1 and k2, and two reaction orders, m and n. The overall reaction order, m + n, is in the range 2.