Induction of alopecia areata in C3H/HeJ mice using polyinosinic-polycytidylic acid (poly[I:C]) and interferon-gamma.

Alopecia areata (AA) is a chronic, relapsing hair-loss disorder that is considered to be a T-cell-mediated autoimmune disease. Several animal models for AA have been created to investigate the pathophysiology and screen for effective therapeutic targets. As C3H/HeJ mice develop AA spontaneously in a low frequency, a novel animal model is needed to establish an AA-like condition faster and more conveniently.

Effects of a calcium phosphate-coated and anodized titanium surface on early bone response.

Purpose: The aim of this study was to evaluate the effectiveness of a calcium phosphate (CaPO4)-coated and anodized titanium surface in vitro and in vivo.

Materials And Methods: A turned surface was employed as a negative control. A sandblasted/acid-etched surface and an anodized surface were used as positive controls, and a CaPO4-coated and anodized (CPA) surface was investigated as the experimental group.

Biomechanical evaluation of dental implants with different surfaces: Removal torque and resonance frequency analysis in rabbits.

Statement Of Problem: Macroscopic and especially microscopic properties of implant surfaces play a major role in the osseous healing of dental implants. Dental implants with modified surfaces have shown stronger osseointegration than implants which are only turned (machined). Advanced surface modification techniques such as anodic oxidation and Ca-P application have been developed to achieve faster and stronger bonding between the host bone and the implant.