Publications by authors named "Jung-Hyun Yoon"

Thread lifting is a popular nonsurgical procedure for skin rejuvenation, utilizing bioabsorbable barbed threads inserted into subcutaneous or deeper structures such as the superficial musculoaponeurotic system. Despite its efficacy, complications such as thread misplacement can occur, leading to adverse outcomes such as dimpling, inflammation, and scar formation. This article presents a clinical case involving a 32-year-old woman with a superficially placed thread following a thread-lifting procedure.

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Purpose: This study explores a self-learning method as an auxiliary approach in residency training for distinguishing between benign and malignant thyroid nodules.

Methods: Conducted from March to December 2022, internal medicine residents underwent three repeated learning sessions with a "learning set" comprising 3000 thyroid nodule images. Diagnostic performances for internal medicine residents were assessed before the study, after every learning session, and for radiology residents before and after one-on-one education, using a "test set," comprising 120 thyroid nodule images.

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Purpose: This study evaluated the educational impact of an artificial intelligence (AI)-based decision support system for breast ultrasonography (US) on medical professionals not specialized in breast imaging.

Methods: In this multi-case, multi-reader study, educational materials, including American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) descriptors, were provided alongside corresponding AI results during training. The AI system presented results in the form of AIheatmaps, AI scores, and AI-provided BI-RADS assessment categories.

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Article Synopsis
  • There is limited research linking breast MRI surveillance to the incidence of advanced second breast cancer in women with a personal history of breast cancer.
  • A study conducted on women who underwent breast cancer surgery between 2009 and 2014 found that those who received MRI surveillance had significantly lower odds of developing advanced second breast cancer compared to those who did not.
  • The findings suggest that surveillance breast MRI may be an effective tool for monitoring women with a personal history of breast cancer, potentially leading to earlier detection and better outcomes.
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Active surveillance (AS) has been widely adopted as an alternative to immediate surgery owing to the indolent nature and favorable outcomes of papillary thyroid microcarcinoma (PTMC). AS is generally recommended for tumors measuring ≤1 cm without aggressive cytological subtypes, risk of gross extrathyroidal extension (ETE), lymph node metastasis (LNM), or distant metastasis. AS requires careful patient selection based on various patient and tumor characteristics, and ultrasound (US) findings.

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Active surveillance (AS) has been widely adopted as an alternative to immediate surgery owing to the indolent nature and favorable outcomes of papillary thyroid microcarcinoma (PTMC). AS is generally recommended for tumors measuring ≤1 cm without aggressive cytological subtypes, risk of gross extrathyroidal extension (ETE), lymph node metastasis (LNM), or distant metastasis. AS requires careful patient selection based on various patient and tumor characteristics, and ultrasound (US) findings.

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Objectives: This study aims to compare outcomes following a negative surveillance MRI study by surgery-MRI interval and investigate factors associated with second breast cancers in women with a personal history of breast cancer (PHBC).

Methods: This retrospective study included 1552 consecutive women (mean age, 53 years) with a PHBC and a negative prevalence surveillance breast MRI result between August 2014 and December 2016. The incidence and characteristics of second breast cancers were reviewed and compared according to surgery-MRI interval (< 3 years vs ≥ 3 years).

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Article Synopsis
  • A survey was conducted among members of the Korean Society of Radiology (KSR) to assess the use, implementation, and needs of artificial intelligence-based software as medical devices (AI-SaMDs) in clinical settings, revealing that 60.3% of respondents had experience using these tools.
  • The most common applications were lesion detection and diagnosis, with high satisfaction rates reported for AI-SaMD performance and its role in improving patient management.
  • Respondents emphasized the need for future development to enhance practice efficiency and quality, while 91.9% agreed on the necessity for KSR-driven education and guidelines for using AI-SaMDs.
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  • This study looked at whether scores from an AI tool can help doctors figure out if a type of breast cancer called DCIS will become more serious after a biopsy.
  • They checked 440 cases of DCIS in women and used special mammogram images analyzed by AI to get these scores.
  • The results showed that higher AI scores, especially over 75%, can help predict if the DCIS will turn into invasive cancer, making it an important tool for doctors.
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Objective: To investigate whether reader training improves the performance and agreement of radiologists in interpreting unenhanced breast magnetic resonance imaging (MRI) scans using diffusion-weighted imaging (DWI).

Materials And Methods: A study of 96 breasts (35 cancers, 24 benign, and 37 negative) in 48 asymptomatic women was performed between June 2019 and October 2020. High-resolution DWI with b-values of 0, 800, and 1200 sec/mm² was performed using a 3.

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Article Synopsis
  • Various US-based risk stratification systems for thyroid nodules are used globally, but inconsistent definitions and malignancy ratings create confusion and complicate comparisons between studies.
  • Interobserver variability in identifying ultrasound characteristics also hinders the consistent application of these systems.
  • In 2018, an international group of 19 experts formed the International Thyroid Nodule Ultrasound Working Group to develop the International Thyroid Imaging Reporting and Data System (I-TIRADS), starting with a lexicon and atlas of ultrasound descriptors for thyroid nodules.
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Introduction: Ultrasonography (US) features of papillary thyroid cancers (PTCs) are used to select nodules for biopsy due to their association with tumor behavior. However, the molecular biological mechanisms that lead to the characteristic US features of PTCs are largely unknown.

Objectives: This study aimed to investigate the molecular biological mechanisms behind US features assessed by radiologists and three convolutional neural networks (CNN) through transcriptome analysis.

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Objective: The aims of the work described here were to evaluate the learnability of thyroid nodule assessment on ultrasonography (US) using a big data set of US images and to evaluate the diagnostic utilities of artificial intelligence computer-aided diagnosis (AI-CAD) used by readers with varying experience to differentiate benign and malignant thyroid nodules.

Methods: Six college freshmen independently studied the "learning set" composed of images of 13,560 thyroid nodules, and their diagnostic performance was evaluated after their daily learning sessions using the "test set" composed of images of 282 thyroid nodules. The diagnostic performance of two residents and an experienced radiologist was evaluated using the same "test set.

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Screening mammography has decreased performance in patients with dense breasts. Supplementary screening ultrasound is a recommended option in such patients, although it has yielded mixed results in prior investigations. The purpose of this article is to compare the performance characteristics of screening mammography alone, standalone artificial intelligence (AI), ultrasound alone, and mammography in combination with AI and/or ultrasound in patients with dense breasts.

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Purpose: To evaluate the stand-alone diagnostic performances of AI-CAD and outcomes of AI-CAD detected abnormalities when applied to the mammographic interpretation workflow.

Methods: From January 2016 to December 2017, 6499 screening mammograms of 5228 women were collected from a single screening facility. Historic reads of three radiologists were used as radiologist interpretation.

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Article Synopsis
  • There is growing interest in using AI for mammographic screening, but its performance needs thorough evaluation before it can be used independently for diagnosis.
  • A systematic review analyzed data from 16 studies involving over a million mammogram examinations to compare AI's performance with that of radiologists in interpreting digital mammography and digital breast tomosynthesis (DBT).
  • Results showed that AI had better standalone performance (higher AUC) in most reader studies on digital mammography and in DBT, though its sensitivity was higher and specificity lower compared to radiologists, indicating promise but also some drawbacks in using AI for screening.
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To assess the performance of deep convolutional neural network (CNN) to discriminate malignant and benign thyroid nodules < 10 mm in size and compare the diagnostic performance of CNN with those of radiologists. Computer-aided diagnosis was implemented with CNN and trained using ultrasound (US) images of 13,560 nodules ≥ 10 mm in size. Between March 2016 and February 2018, US images of nodules < 10 mm were retrospectively collected at the same institution.

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Objective: Mammographic density is an independent risk factor for breast cancer that can change after neoadjuvant chemotherapy (NCT). This study aimed to evaluate percent changes in volumetric breast density (ΔVbd%) before and after NCT measured automatically and determine its value as a predictive marker of pathological response to NCT.

Materials And Methods: A total of 357 patients with breast cancer treated between January 2014 and December 2016 were included.

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Purpose: This study aimed to investigate radiomics analysis of ultrasonographic images to develop a potential biomarker for predicting lymph node metastasis in papillary thyroid carcinoma (PTC) patients.

Materials And Methods: This study included 431 PTC patients from August 2013 to May 2014 and classified them into the training and validation sets. A total of 730 radiomics features, including texture matrices of gray-level co-occurrence matrix and gray-level run-length matrix and single-level discrete two-dimensional wavelet transform and other functions, were obtained.

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Background: Mammography yields inevitable recall for indeterminate findings that need to be confirmed with additional views.

Purpose: To explore whether the artificial intelligence (AI) algorithm for mammography can reduce false-positive recall in patients who undergo the spot compression view.

Material And Methods: From January to December 2017, 236 breasts from 225 women who underwent the spot compression view due to focal asymmetry, mass, or architectural distortion on standard digital mammography were included.

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Purpose: To evaluate and compare the diagnostic outcomes of ultrasonography (US)-guided fine needle aspiration (FNA) and core needle biopsy (CNB) performed on the same thyroid nodule using a surgical specimen for direct comparison.

Materials And Methods: We included 89 thyroid nodules from 88 patients from February 2015 to January 2016. The inclusion criterion was thyroid nodules measuring ≥ 20 mm (mean size: 40.

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Objective: Improved molecular testing for common somatic mutations and the identification of mRNA and microRNA expression classifiers are promising approaches for the diagnosis of thyroid nodules. However, there is a need to improve the diagnostic accuracy of such tests for identifying thyroid cancer. Recent findings have revealed a crucial role of long non-coding RNAs (lncRNAs) in gene modulation.

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