A randomized controlled trial comparing liquid skin adhesives and staplers for surgical wound management.

Purpose: Despite the widespread use of liquid skin adhesives (LSA), concerns persist regarding the increase in wound care costs. This study aimed to investigate the cost-effectiveness of LSA for surgical wound management.

Methods: In this prospective, open-label, single-center randomized controlled trial, adults aged 19 years and older who were scheduled for elective minimally invasive colorectal surgeries were included.

Effective Management of Thread Misplacement in Thread Lifting Procedures: A Clinical Case Utilizing the Hook for Extraction.

Thread lifting is a popular nonsurgical procedure for skin rejuvenation, utilizing bioabsorbable barbed threads inserted into subcutaneous or deeper structures such as the superficial musculoaponeurotic system. Despite its efficacy, complications such as thread misplacement can occur, leading to adverse outcomes such as dimpling, inflammation, and scar formation. This article presents a clinical case involving a 32-year-old woman with a superficially placed thread following a thread-lifting procedure.

Air-Stable Mid-Infrared Sensitive Cation-Exchanged Silver-Doped Mercury Telluride Nanocrystal.

We present an air-stable mid-infrared (mid-IR) Ag-doped HgTe (Ag-HgTe) colloidal quantum dots (CQDs) synthesized by a newly developed cation-exchange (CE) method in solution phase and mid-IR diode sensors fabricated with the as-synthesized Ag-HgTe quantum dots (QDs). The cation-exchanged p-doped Ag-HgTe CQDs are used for the p-n junction formation with a n-doped HgTe CQDs. Surprisingly, the Ag-HgTe CQDs sustain the optical and physical properties in the colloidal phase under ambient conditions for 900 days.

The complete chloroplast genome of (Liliaceae) in Mongolia.

(L.) Besser ex Baker (1874) is distributed throughout China, Mongolia, and Russia (Siberia). This study reports the complete chloroplast genome sequence of based on high-throughput sequencing.

Quantitative and Qualitative Analysis of Clinical Trial Acronyms From Surgical Journals.

Introduction: Acronyms, the short form of a word or phrase, are commonly used in medical research to identify studies. However, their usage and quality assessment in surgical journals are unclear. This study aimed to determine the impact of identifying acronyms for clinical studies on the number of citations by comparing studies published in surgical and medical journals.

Enhancing diagnostic accuracy of thyroid nodules: integrating self-learning and artificial intelligence in clinical training.

Purpose: This study explores a self-learning method as an auxiliary approach in residency training for distinguishing between benign and malignant thyroid nodules.

Methods: Conducted from March to December 2022, internal medicine residents underwent three repeated learning sessions with a "learning set" comprising 3000 thyroid nodule images. Diagnostic performances for internal medicine residents were assessed before the study, after every learning session, and for radiology residents before and after one-on-one education, using a "test set," comprising 120 thyroid nodule images.

Conceptualising the everyday harm experienced by people with cognitive disability: A scoping review of microaggression and emotional and psychological abuse.

Background: Many people with disability experience harm in everyday interactions that can leave them feeling insulted, degraded, silenced, or rejected. We adopt the term "everyday harm" to describe this underexplored form of harm.

Method: The purpose of this scoping review was to assess how the literature on microaggression and emotional and psychological abuse contributes to an understanding of everyday harm and misrecognition.

Optical Coherence Tomography Image Enhancement and Layer Detection Using Cycle-GAN.

Variations in image clarity across different OCT devices, along with the inconsistent delineation of RNFL boundaries, pose a challenge to achieving consistent diagnoses for glaucoma. Recently, deep learning methods such as GANs for image transformation have been gaining attention. This paper introduces deep learning methods to transform low-clarity images from one OCT device into high-clarity images from another, concurrently estimating the retinal nerve fiber layer (RNFL) segmentation lines in the enhanced images.

Improving breast ultrasonography education: the impact of AI-based decision support on the performance of non-specialist medical professionals.

Purpose: This study evaluated the educational impact of an artificial intelligence (AI)-based decision support system for breast ultrasonography (US) on medical professionals not specialized in breast imaging.

Methods: In this multi-case, multi-reader study, educational materials, including American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) descriptors, were provided alongside corresponding AI results during training. The AI system presented results in the form of AIheatmaps, AI scores, and AI-provided BI-RADS assessment categories.

GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma.

Backgrounds/aims: Hepatocellular carcinoma (HCC) is characterized by high recurrence and mortality, necessitating the identification of reliable biomarkers. In this study, we aimed to identify the predictive gene signatures for HCC recurrence and evaluate the efficiency of GULP PTB domain-containing engulfment adaptor 1 (GULP1) as a predictive and diagnostic marker and therapeutic target for HCC.

Methods: We analyzed genomic datasets from The Cancer Genome Atlas and Gene Expression Omnibus databases via least absolute shrinkage and selection operator Cox regression and 10-fold cross-validation, leading to the development of a 15-gene risk score model, which was validated using three independent datasets.

Flexible Synaptic Memristors With Controlled Rigidity in Zirconium-Oxo Clusters for High-Precision Neuromorphic Computing.

Flexible memristors are promising candidates for multifunctional neuromorphic computing applications, overcoming the limitations of conventional computing devices. However, unpredictable switching behavior and poor mechanical stability in conventional memristors present significant challenges to achieving device reliability. Here, a reliable and flexible memristor using zirconium-oxo cluster (ZrOOH(OMc)) as the resistive switching layer is demonstrated.

[How to Achieve Diversity, Equity, and Inclusion in The Korean Society of Gastroenterology?].

With the increasing emphasis on diversity, equity, and inclusion (DEI) in organizations and institutions, academic societies in gastroenterology and hepatology are beginning to take actionable steps toward achieving DEI. The successful implementation of DEI initiatives leads to excellence in the field, improved patient outcomes, particularly in areas where health disparities are prevalent, and advances in the gastrointestinal discipline. Such implementation also results in a workforce that better reflects the growing diversity of the population.

NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis.

Background: Gastric cancer remains a significant global health challenge, characterized by poor prognosis and high mortality rates. Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. The transcription factor NKX6.

Long-term high fat diet aggravates the risk of lung fibrosis and lung cancer: transcriptomic analysis in the lung tissues of obese mice.

Background: Previous studies reported significant relationships between obesity and pulmonary dysfunction. Here, we investigated genetic alterations in the lung tissues of high fat diet (HFD) induced obese mouse through transcriptomic and molecular analyses.

Methods: Eight-week-old male C57BL/6J mice were fed either a normal chow diet (NCD) or HFD for 12 weeks.

Korean Gastric Cancer Association-Led Nationwide Survey on Surgically Treated Gastric Cancers in 2023.

Purpose: Since 1995, the Korean Gastric Cancer Association (KGCA) has been periodically conducting nationwide surveys on patients with surgically treated gastric cancer. This study details the results of the survey conducted in 2023.

Materials And Methods: The survey was conducted from March to December 2024 using a standardized case report form.

Controlled Structural Activation of Iridium Single Atom Catalyst for High-Performance Proton Exchange Membrane Water Electrolysis.

Iridium single atom catalysts are promising oxygen evolution reaction (OER) electrocatalysts for proton exchange membrane water electrolysis (PEMWE), as they can reduce the reliance on costly Ir in the OER catalysts. However, their practical application is hindered by their limited stability during PEMWE operation. Herein, we report on the activation of Ir-doped CoMnO in acidic electrolyte that leads to enhanced activity and stability in acidic OER for long-term PEMWE operation.

Registered Nurse Staffing and Inpatient Outcomes in Korean Long-Term Care Hospitals.

Background/objectives: There is a relative lack of specific research on registered nurse (RN) staffing in long-term care hospitals in the Republic of Korea. This study investigated the association between RN staffing levels and inpatient outcomes in long-term care hospitals in the Republic of Korea.

Methods: Nationwide data of long-term care hospitals from the Health Insurance Review and Assessment Services website were used to analyze the association between registered nurse staffing levels and 7 inpatient outcome indicators.

Cooperative Brønsted Acid-Single Atom Photocatalysis in Metal-Organic Framework.

Enzymes, composed of earth-abundant elements, outperform conventional heterogeneous photocatalysts in hydrogen production due to the dual-site cooperation between adjacent active metal sites and proton-transferring ligands. However, the realization of such dual-site cooperation in heterogeneous catalytic systems is hindered by the challenges in the precise construction of cooperative active sites. In this study, we present the design of a structurally tuned metal-organic framework (MOF) photocatalyst that incorporates cooperative Brønsted acid-single atom catalytic sites.

Autophagic signatures in peripheral blood mononuclear cells from Parkinson's disease patients.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor impairments and the accumulation of misfolded α-synuclein. Dysregulation of the autophagy-lysosomal pathway (ALP), responsible for degrading misfolded proteins, has been implicated in PD pathogenesis. However, current diagnostic approaches rely heavily on motor symptoms, which occur due to substantial neurodegeneration, limiting early detection and intervention.

Unintentional medication discrepancies at care transitions: prevalence and their impact on post-discharge emergency visits in critically ill older adults.

Background: Unintentional medication discrepancies during care transitions pose a significant risk for medication errors, particularly in critically ill older patients. This study aimed to investigate the prevalence of such discrepancies during care transitions and their impact on post-discharge emergency department (ED) visits in this patient population.

Methods: This retrospective cross-sectional study included patients aged 65 and older who were on chronic medications and admitted to the intensive care units of emergency departments (ED-ICUs) between 2019 and 2020.

Gastric emptying time and its correlation with cardiac MIBG in body-first and brain-first subtype Parkinson's disease.

Introduction: Recently, "body-first" and "brain-first" subtype in Parkinson's disease (PD) was proposed based on the propagation of α-synuclein. In isolated RBD considered as a premotor stage of body-first PD, α-synuclein was supposed to originate in the enteric nervous system and spreads via autonomic nervous system. Therefore, we hypothesized that body-first PD is more likely to have a delayed gastric emptying time and reduced cardiac sympathetic denervation.

Standardized Ultrasound Evaluation for Active Surveillance of Low-Risk Thyroid Microcarcinoma in Adults: 2024 Korean Society of Thyroid Radiology Consensus Statement.

Active surveillance (AS) has been widely adopted as an alternative to immediate surgery owing to the indolent nature and favorable outcomes of papillary thyroid microcarcinoma (PTMC). AS is generally recommended for tumors measuring ≤1 cm without aggressive cytological subtypes, risk of gross extrathyroidal extension (ETE), lymph node metastasis (LNM), or distant metastasis. AS requires careful patient selection based on various patient and tumor characteristics, and ultrasound (US) findings.