Publications by authors named "Jung Seok Choi"
Resting-state EEG microstate analysis of internet gaming disorder and alcohol use disorder.
Dialogues Clin Neurosci
November 2024
Article Synopsis
- - The study compared neurophysiological characteristics of internet gaming disorder (IGD), alcohol use disorder (AUD), and healthy controls (HCs) using resting-state EEG to understand addiction better.
- - Involving 199 young adults, the research found that AUD patients had lower microstate features compared to those with IGD, indicating different brain activity patterns associated with each disorder.
- - The results suggested that specific EEG microstate characteristics could serve as neuromarkers to distinguish between addictive disorders and assess their underlying mechanisms.
Article Synopsis
- Fetal bovine serum (FBS) is expensive and raises animal welfare concerns since it's harvested from pregnant cows during slaughter.
- This study developed an alternative FBS substitute using blood from slaughterhouse waste, which proved to be effective for cell culture.
- The substitute not only enhanced muscle growth in lab experiments but could also reduce costs by around 61%, making it a promising option for cultured meat production and other biotechnological applications.
Article Synopsis
- - The study investigates the connection between serum CART levels and internet gaming disorder (IGD), a condition that has become more common due to the growth of online gaming.
- - Researchers found that individuals with IGD had lower serum CART levels compared to healthy controls, along with higher scores in depression and anxiety.
- - The findings suggest that lower CART levels may indicate a higher risk for developing IGD, thereby positioning CART as a potential biomarker for the disorder.
Article Synopsis
- - Researchers examined the effects of adding L. powder (C) to Tteokgalbi, a traditional Korean meat dish, comparing different concentrations (0%, 1%, 2%, 4%) and ascorbic acid as a control.
- - Higher levels of C led to changes in the meat's moisture, protein, fat, and carbohydrate content, affecting its color, texture, and cooking properties; particularly, the water-holding capacity decreased, causing more cooking loss.
- - The addition of C not only enhanced nutritional aspects like phenolic and flavonoid content but also resulted in lower microbial counts after storage, indicating its potential as a natural additive in meat products.
This study aimed to explore the predictors of posttraumatic stress disorder (PTSD) in women who have recently experienced sexual assault, by examining psychological and neurophysiological factors using a prospective design with resting-state electroencephalogram (EEG) functional connectivity. The study enrolled 33 women who had been recently traumatized by sexual assault and conducted assessments within a month of the trauma. These survivors were evaluated for PTSD three months later and were classified into two groups: PTSD positive (n = 12) and PTSD negative (n = 21).
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- E. cava, a brown seaweed from East Asia, contains beneficial compounds such as polysaccharides and polyphenols, with fucoidan being a key ingredient in food products.
- The study extracted crude polysaccharides (ECC_CPS) from this seaweed, which significantly improved the growth and migration of muscle satellite cells (HMSCs) during laboratory tests.
- ECC_CPS not only enhanced cell proliferation but also promoted differentiation, indicating its potential as a functional additive in cultured meat production.
Article Synopsis
- The study aimed to explore the differences and similarities between internet gaming disorder (IGD), classified as a behavioral addiction (BA), and alcohol use disorder (AUD), classified as a substance use disorder (SUD), through neuroscientific research and machine learning (ML) techniques.! -
- Researchers developed three ML models that distinguished between IGD, AUD, and healthy controls, using various feature sets, including neurophysiological data from EEG and neuropsychological factors like sex, age, and mental health traits.! -
- The results showed that the multimodal ML model was most effective in classifying IGD and AUD, revealing unique neurophysiological characteristics for IGD and emphasizing the significance of factors like sex and
Article Synopsis
- Resting-state brain activity may influence task performance, but research combining fMRI and ERPs on addictive disorders like internet gaming disorder (IGD) is limited.
- This study compared brain activity between 26 IGD patients and 27 healthy controls using resting-state fMRI metrics and ERP components.
- Results showed IGD patients had altered brain activity patterns, indicating challenges with cognitive function and sensory processing, contributing to a better understanding of IGD's neurobiological mechanisms.
Fetal bovine serum (FBS) is an extremely important culture growth supplement, accounting for approximately 60 % of cell-culture-media costs; therefore, lowering FBS-acquisition costs for the industrialization of cultured meat is imperative. This study attempted to produce an FBS substitute using discarded livestock by-products, with particular focus on formulating a product with a composition similar to that of FBS to improve effectiveness. However, to date, no study has precisely analyzed the commercial components of FBS, and this study is the first to compare the chemical composition of FBS and commercially available horse serum purchased from the United States or Europe with that of FBS substitutes developed by our team.
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- * The cultured meat production involves four main steps: isolating muscle cells, proliferating them, differentiating into myotubes, and validating the results.
- * The study highlights enhanced techniques that led to better cell isolation, double the proliferation efficiency, and significant improvements in myotube formation, ultimately aiming to create cheaper and safer cultured meat.
Stress and resilience are involved in the pathophysiology of addictive disorders, and heart rate variability (HRV) is an index of an individual's global capability to regulate psychological responses. In this study, we aimed to identify transdiagnostic and disorder-specific markers in people with addictive disorders by analyzing resting-state HRV and associations with the levels of stress and resilience. We compared relevant data between patients with internet gaming disorder (IGD) and/or alcohol use disorder (AUD) and healthy controls (HCs).
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- A scoping review was conducted to analyze the relationship between emerging digital gambling-like activities, such as loot boxes and esports betting, and traditional gambling and video gaming behaviors.
- The review included 38 empirical studies, revealing that participation in gambling-like activities is linked to increased mental distress, impulsivity, and a positive association with both gambling and gaming behaviors.
- Identified gaps in the research highlight the need for more diverse methodologies and participant demographics, particularly in understanding skin betting and token wagering.
Article Synopsis
- ATF7 is a transcription factor that helps form heterochromatin in normal conditions, but its role during porcine embryonic development is not well understood.
- * In this study, researchers observed that ATF7 accumulates in the nucleus and associates with heterochromatin after a certain developmental stage; its knockdown led to reduced embryo formation and cell numbers.
- * The findings suggest that stress affects ATF7's function, highlighting its importance in regulating gene expression and embryo quality during early development.
Objective: Temperament is close to susceptibility to stress and the increased level of stress may lead problematic smartphone use (PSU). In this study, the relationships between harm avoidance (HA) as a personality trait, daily traits, and PSU in children and adolescents were investigated.
Methods: At baseline, all participants (184 children and adolescents, mean age 13.
Article Synopsis
- The review summarizes studies on fetal bovine serum (FBS) in vertebrates and examines its role in commercializing cultured meat.
- It highlights that while FBS contains various essential components, research on its composition compared to adult blood is limited, complicating efforts to replace it.
- The review emphasizes the need for affordable and suitable alternatives to FBS to advance the industrial production of cultured meat successfully.
Article Synopsis
- The study analyzed EEG patterns in 140 participants, including 76 with Internet gaming disorder (IGD) and 64 healthy controls, focusing on gaming habits and genres.
- IGD patients playing single games (SG) exhibited higher beta activity, suggesting a connection to behavioral inhibition, while those playing first-person shooters (FPS) showed increased delta power linked to the severity of IGD.
- Notable differences in brain wave coherence were found in the left frontoparietal region among gamers, indicating a relationship between certain gaming genres and impairments in visuospatial working memory.
Article Synopsis
- - The study addresses Internet gaming disorder (IGD) by exploring machine learning techniques to improve its prediction and intervention methods through analyzing multimodal neuroimaging data like PET and EEG.
- - Utilizing a multiple-kernel support vector machine (MK-SVM), the researchers achieved a prediction accuracy of 86.5%, outperforming standard methods like random forest and boosting in distinguishing between IGD patients and healthy controls.
- - Results indicated that clinical variables significantly contributed to the prediction model's accuracy, highlighting the effectiveness of combining different data sources for better IGD assessment and prediction.
Article Synopsis
- Excessive alcohol consumption affects the brain by altering neurotransmitter and hormonal systems, impacting areas like the hippocampus and forebrain.
- The study investigated how ethanol exposure influences the expression of coding and noncoding RNAs in Neuro2a neuroblastoma cells over 24 and 72 hours, revealing significant changes in cell proliferation and RNA expression.
- Results showed that chronic exposure to ethanol (100 mM for 72 hours) reduced cell growth and led to over 1700 RNA transcripts' changes, particularly involving long noncoding RNAs, enhancing the understanding of alcohol's neurobiological impacts.
Article Synopsis
- This text serves as a correction for a previously published article, identified by its DOI: 10.3389/fpsyt.2021.685964.
- The correction addresses specific errors or inaccuracies found in the original article to ensure the integrity of the research.
- It emphasizes the importance of accurate reporting in academic publications to maintain credibility in the field of psychiatry.
Background: The present study assessed the impact of different types of breast surgery on rates of psychological disorders in breast cancer patients.
Methods: This nationwide cohort study, based on Korean Health Insurance Review and Assessment Service claims data, included 26,259 breast patients who underwent surgery from June 1, 2017, to December 31, 2018. Associations between the incidence of psychological disorders and variables were evaluated by time dependent Cox regression analyses.
Article Synopsis
- * A study involving 99 young adults showed that those with alcohol use disorder (AUD) and Internet gaming disorder (IGD) experienced higher stress levels, lower resilience, and impaired cognitive functions compared to healthy controls (HCs).
- * Findings indicated that individuals with AUD had notably elevated KYN levels and altered KYN/KYNA ratios, suggesting that the KYN pathway plays a vital role in the effects of stress on addiction, highlighting it as a potential target for treatment.
Review of technology and materials for the development of cultured meat.
Crit Rev Food Sci Nutr
November 2023
Article Synopsis
- - Cultured meat technology aims to address issues associated with traditional meat production, such as poor breeding environments, wastewater management, methane emissions, and ethical concerns regarding animal welfare.
- - The review discusses the current commercialization status of cultured meat, its production methods, and the challenges faced, including the need for appropriate materials and cell culture techniques.
- - Despite advancements like the use of scaffolding and 3D printing for more meat-like structures, reducing production costs and developing suitable edible materials remain significant hurdles in making cultured meat a viable food option.