Radiat Prot Dosimetry
August 2013
As of the end of 2010, there were 20 commercially operating nuclear reactors in Korea. Releases of radioactive effluents from nuclear power plants (NPPs) have increased continuously; the total radioactivity of effluent amount released in 2010 was 547.12 TBq.
View Article and Find Full Text PDFSince the first Korean nuclear power plant (NPP), Kori 1, commenced operation in 1978, a total of 21 NPPs had been put into operation in Korea by the end of 2011. Radiation doses of NPP workers have been periodically evaluated and controlled within the prescribed dose limit. Radiation dose assessment is carried out monthly by reading personal dosemeters for external radiation exposure, which have traceability in compliance with strict technical guidelines.
View Article and Find Full Text PDFBackground: We previously showed that an Epstein-Barr virus (EBV)-based plasmid, pEBVGFP, exerts prolonged gene expression in porcine neonatal pancreatic cell clusters (NPCCs). In this study, the mechanism underlying this was investigated.
Methods: GFP expression was analyzed in porcine cells transfected with pEBVGFP by FACS analysis and confocal microscopy.
Combined treatment with the medicinal mushroom Ganoderma lucidum and the herb Duchesnea chrysantha extracts (GDE) causes a synergistic induction of mitochondrial damage and apoptosis in HL-60 cells. GDE treatment is selectively toxic to HL-60 leukemia cells whereas no cytotoxic effect is observed in normal peripheral blood mononuclear cells. GDE-induced apoptosis is associated with Bcl-2 down-regulation, Bax translocation, mitochondrial cytochrome c release and caspase-3 activation, suggesting that apoptosis by this combination occurs through the mitochondria-dependent pathway.
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