Enhanced Stability and Compatibility of Montelukast and Levocetirizine in a Fixed-Dose Combination Monolayer Tablet.

The purpose of this study was to enhance the stability of montelukast and levocetirizine for the development of a fixed-dose combination (FDC) monolayer tablet. To evaluate the compatibility of montelukast and levocetirizine, a mixture of the two drugs was prepared, and changes in the appearance characteristics and impurity content were observed in a dry oven at 60 °C. Excipients that contributed minimally to impurity increases were selected to minimize drug interactions.

Substantial Improvement of Color-Rendering Properties of Conventional White LEDs Using Remote-Type Red Quantum-Dot Caps.

A new type of remote red quantum-dot (QD) component was designed and fabricated to improve the color-rendering properties of conventional white LED (light-emitting diode) lightings. Based on an optical simulation, the rectangular cavity-type QD cap was designed with an opening window on the top surface. Red QD caps were fabricated using a typical injection molding technique and CdSe/ZnS QDs with a core/shell structure whose average size was ~6 nm.