Composition, antioxidant capacity, intestinal, and immunobiological effects of oregano (Lippia palmeri Watts) in goats: preliminary in vitro and in vivo studies.

This study investigated Lippia palmeri Watt (oregano) phytochemical compounds, their antioxidant capacity, and immunological effects on goat peripheral blood leukocytes (PBL), and on the presence of intermediate polar compounds in goat feces fed dietary oregano. The polar and nonpolar fractions of L. palmeri W.

Concentric-flow electrokinetic injector enables serial crystallography of ribosome and photosystem II.

We describe a concentric-flow electrokinetic injector for efficiently delivering microcrystals for serial femtosecond X-ray crystallography analysis that enables studies of challenging biological systems in their unadulterated mother liquor. We used the injector to analyze microcrystals of Geobacillus stearothermophilus thermolysin (2.2-Å structure), Thermosynechococcus elongatus photosystem II (<3-Å diffraction) and Thermus thermophilus small ribosomal subunit bound to the antibiotic paromomycin at ambient temperature (3.

The crossed response inhibition task in Parkinson's disease: disinhibition hyperkinesia.

Patients with Parkinson's disease (PD) have dysfunction in frontal-basal ganglia networks. Many of these patients have difficulties with mental processing speed, response inhibition, and shifting between different conceptual sets, suggesting frontal-executive dysfunction. Since frontal lobe dysfunction is associated with disengagement deficits such as perseveration and echopraxia we wanted to learn if patients with PD demonstrated defective response inhibition.

Efficacy and safety of Etanercept, high-dose intravenous gammaglobulin and plasmapheresis combined therapy for lupus diffuse proliferative nephritis complicating pregnancy.

We report one case of pregnancy-onset severe diffuse proliferative nephritis in a patient with systemic lupus erythematosus (SLE), who was successfully treated with a combination of anti-tumour necrosis factor (TNF)-alpha, plasmapheresis and high-dose intravenous gammaglobulin. No flares were observed either in clinical symptoms or in laboratory examinations during pregnancy or after delivery. Her autoantibodies except fluorescent anti-nuclear antibodies were negative.

Haemodialysis dose, extracellular volume control and arterial hypertension.

Patients with chronic renal failure on periodical dialysis frequently are hypertensive. This frequency has increased in relation to the liberalization of diet and to short dialysis with a high sodium concentration in the dialysate. Although various factors influence the pathogenesis of this type of hypertension, volume overload is the most significant.

The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study Group.

Acute renal failure (ARF) is at a crossroads between nephrology and intensive care medicine. However, there seems to be wide differences between the ARF observed in the intensive care unit (ICU) compared to that observed in other areas of the hospital, particularly when examining the mortality rate. Among the ICU patients the 70% mortality rate is higher to the 50% found in an overall series of studies.

Effect of zinc treatment on serum thyroid hormones in uremic patients under peritoneal dialysis.

In order to evaluate the effect of zinc (Zn) deficiency on thyroid abnormalities in chronic renal failure, a Zn supplement (100 mg/day, p.o.) was given for four weeks to eight uremic patients under peritoneal dialysis.

HbA1, height velocity and weight gain as indicators of metabolic control in type I diabetic children. A 5 year survey.

The purpose of this study was to evaluate the metabolic control of the type I diabetic patients seen from 1984 to 1988. We analyzed the results of HbA1, height velocity and weight gain. Results showed that from 1984 1985 a 90% of diabetics were in poor metabolic control with HbA1 > 11% (good control < 11%).

[Membranous nephritis after renal transplantation].

8 cases of membranous glomerulonephritis (MG) after renal transplants (RT) are presented; one being a recurrence of the original disease and the other 7 due to a different cause of renal insufficiency. The total incidence of MG after transplantation was 1.63%; 1.

Renal metabolism during four types of lactic acidosis in the dog including anoxia.

The present study was undertaken to evaluate the metabolic response of the kidney to lactic acidosis. Four types of lactic acidosis were induced in the dog: infusion of lactic acid, infusion of lactic acid with phenformin, administration of phenformin alone, and hypoxia by breathing 95% nitrogen. In all groups of animals, the same degree of acidosis was observed with plasma bicarbonate ranging from 12.

The metabolic response of the kidney to acute sodium lactate alkalosis.

In vivo studies were performed in the dog to verify if sodium lactate had an important effect on the metabolism of glutamine by the kidney. The animals were infused with 0.6 M sodium lactate to induce acute metabolic alkalosis with plasma bicarbonate of 29.

Leucopenia, hypoxia and complement activation in haemodialysis. Three unrelated phenomena.

Acute, transient leucopenia occurs in uraemic patients during the first minutes of haemodialysis, haemofiltration and ultrafiltration, and this leucopenia depends on the membrane used: maximal with cuprophan, less marked using cellulose acetate in haemofiltration and minimal with polyacrylonitrile. Complement activation was noted in all dialysis procedures except ultrafiltration. However, no correlation was found between the intensity of the complement activation and the degree of leucopenia.

[Contribution to acid-base metabolism in hypertonic dehydration by the study of "fraction R" (underterminate anions) (author's transl)].

A study on the value of "R fraction" of plasma electrolites (undetermined anions), in order to know better the metabolic acidosis of the hypertonic dehydration is achieved. "R fraction" value was obtained by the formulae: R fraction = plasma N+ --(plasma Cl- + plasma HCO3-). The mean values in patients with hypertonic dehydration was: 12.

[Metabolic evolution of hypertonic dehydration with combined treatment of fluidotherapy and peritoneal dialysis: revision of 22 infants (author's transl)].

Metabolic evolution of osmolarity, natraemia, chloremia, kaliemia and uremia of 22 infants with severe hypertonic dehydration, treated with fluidotherapy and peritoneal dialysis, is revised. Peritoneal dialysis was prepared in accordance with a special method for this metabolic condition. The serie was divided into two groups, according to initial value of natraemia: more or less than 170 mEq.

[Metabolic evolution of hypertonic dehydration treated with fluidotherapy: revision of 40 infants (author's transl)].

Authors study the metabolic evolution of osmolarity, natraemia, chloremia, kaliemia and uremia of 40 infants with hypertonic dehydration. They divide the serie into two groups in accordance with initial value of natraemia: more or less than 170 mEq./l.

[Treatment and evolution of shock and acidosis in hypertonic dehydration (author's transl)].

Authors analyse treatment and clinical and analytical evolution of 80 patients with hypertonic dehydration, depending on shock and acidosis. Several considerations concerning treatment and its' influence on evolution of different patients, emphasizing both therapeutic methods: with or without use of peritoneal dialysis, according to the values of initial natraemia, are made.