Publications by authors named "Junaid Banday"
Article Synopsis
- The study showcases a new method for synthesizing α-substituted propargylamides and β-acylamino ketones without using metals, leveraging nitriles, aldehydes, and terminal alkynes.
- It utilizes BF·EtO as a Lewis acid, which provides greater control over the reaction outcomes by adjusting its concentration for better selectivity and product formation.
- This method shows strong compatibility with various nucleophiles, allowing for the creation of multiple useful compounds, enhancing tools in organic chemistry synthesis.
In a continuing effort to explore the structural diversity and pharmacological activities of natural products based scaffolds, herein, we report the isolation, synthesis, and structure determination of cannabidiol and its derivatives along with their cytotoxic activities. Treatment of cannabidiol () with acid catalyst POCl afforded a new derivative along with six known molecules -, and, . The structure of was elucidated by extensive spectroscopic analyses and DFT calculations of the NMR and ECD data.
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- Neuropathic pain is a tough type of pain that keeps coming back and doesn’t get better with regular treatments.
- Cannabinoids, which are substances found in cannabis plants, may help reduce this pain by working with the body's endocannabinoid system.
- A study found that certain cannabinoids effectively stopped a specific signaling pathway in the body that is related to pain, suggesting they could be useful in treating neuropathic pain.