Publications by authors named "Junaid Anwar"
: Hepatocellular carcinoma (HCC) is a prevalent liver cancer with poor prognosis, often linked to hepatitis B (HBV) and C (HCV) infections. This meta-analysis evaluates the efficacy of immunotherapy in HCC, particularly in cases arising from viral hepatitis. : In adherence to PRISMA Statement 2020 guidelines, the immunotherapeutic outcomes comprised objective response rate (ORR), progression-free survival (PFS), and overall survival (OS).
View Article and Find Full Text PDFUnilateral choroidal metastases as an unusual presentation of small cell lung cancer.
Proc (Bayl Univ Med Cent)
June 2024
The choroid, rich in vasculature, is a common site for ocular metastases, predominantly from breast and lung cancer. Unlike breast cancer, which may cause bilateral involvement, lung cancer typically leads to unilateral lesions. Adenocarcinoma is the primary lung cancer subtype associated with choroidal metastasis, while small cell lung cancer (SCLC) infrequently involves the choroid.
View Article and Find Full Text PDFBackground: Gastrointestinal (GI) cancers are the third leading cause of cancer-related mortality worldwide. Disparities in healthcare frequently stem from variations in socioeconomic status (SES). This study investigated the influence of socioeconomic factors such as gender, race, age, and geography on time to treatment initiation (TTI) and survival outcomes.
View Article and Find Full Text PDFArticle Synopsis
- Critical limb-threatening ischemia (CLTI) is a serious health problem that can cause the loss of a limb and affect a person's life a lot.
- This study looked at two treatment options, surgery and endovascular therapy, to see which one is better for CLTI patients.
- Results showed that while surgery might be better for preventing major limb issues, endovascular therapy leads to fewer heart problems and has less risk for complications and shorter hospital stays.
Background: Pancreatic cancer remains a lethal malignancy with a 5-year survival rate below 6% and about 500,000 deaths annually worldwide. Pancreatic adenocarcinoma, the most prevalent form, is commonly associated with diabetes, chronic pancreatitis, obesity, and smoking, mainly affecting individuals aged 60 to 80 years. This systematic review aims to evaluate the efficacy of immunotherapeutic approaches in the treatment of pancreatic cancer.
View Article and Find Full Text PDFArticle Synopsis
- Stage IV gastric cancer patients with Krukenberg tumors often have poor survival, typically less than 2 years, and their treatment is not standardized, especially regarding the effectiveness of oophorectomy.
- A systematic review and meta-analysis of 1502 patients showed that overall survival (OS) was significantly improved with surgical resection (12.8 months) and combined chemotherapy and surgery (16.2 months) compared to standard chemotherapy alone (6.7 months).
- These findings suggest that surgical intervention alongside chemotherapy may enhance survival outcomes for patients with gastric cancer and ovarian metastases, guiding clinical decisions and future research.
Utilizing the comprehensive Nationwide Inpatient Sample (NIS) database, we examined the impact of thrombotic thrombocytopenic purpura (TTP) on the outcomes of patients with coronavirus disease-19 (COVID-19), emphasizing the potential role of the ADAMTS13 enzyme in disease pathogenesis and evolution. We analyzed extensive data from the NIS database using STATA v.14.
View Article and Find Full Text PDFBackground: Healthcare providers may improve healthcare delivery and make it available to more people by combining advanced technologies with high-quality network services. In this regard, telemedicine has improved healthcare providers' ability to provide services for a large number of individuals without their physical presence. Pakistan's healthcare system is a mix of government infrastructure, parastatal healthcare, the private sector, civil society, and charitable contributions.
View Article and Find Full Text PDF