Publications by authors named "Jun-peng Deng"
Article Synopsis
- The study looked at using pelvic MRI and a special biopsy method called TRUS-guided TTMB to find out if men have prostate cancer.
- 164 men took part, and they were grouped based on their PSA levels, which help doctors know how likely they are to have cancer.
- The results showed that the method was safe and effective, with most men getting accurate results and only a few having minor issues afterward.
A series of novel anthracene L-rhamnopyranosides compounds were designed and synthesized and their anti-proliferative activities on cancer cell lines were investigated. We found that one derivative S-8 (EM-d-Rha) strongly inhibited cell proliferation of a panel of different human cancer cell lines including A549, HepG2, OVCAR-3, HeLa and K562 and SGC-790 cell lines, and displayed IC50 values in low micro-molar ranges, which are ten folds more effective than emodin. In addition, we found EM-d-Rha (3-(2",3"-Di-O-acetyl-α-L-rhamnopyranosyl-(1→4)-2',3'-di-O-acetyl-α-L-rhamnopyranosyl)-emodin) substantially induced cellular apoptosis of HepG2 and OVCAR-3 cells in the early growth stage.
View Article and Find Full Text PDF