Publications by authors named "Jun-lian Yang"
Article Synopsis
- The study investigates how human adenovirus (HAdV) affects lipid metabolism in infected patients, focusing on those with pneumonia and upper respiratory tract infections (URTI).
- Researchers analyzed blood samples from 35 patients during acute and recovery stages, finding that most differential metabolites were lipids, particularly in the sphingolipid metabolism pathway.
- The results indicate that increased levels of ceramide and lactosylceramide in pneumonia patients suggest that targeting lipid metabolism could be a potential treatment strategy against HAdV infections.
Objectives: The changes in metabolism by human adenovirus (HAdV) infection was unclear. The potential mechanism of HAdV-7 causing acute respiratory tract infection was explored.
Methods: Totally 35 patients with HAdV-7 infection, 32 asymptomatic cases with HAdV-7 and 14 healthy controls were enrolled from an outbreak of HAdV-7 in the army.
[The comparison between HIV-infected patients' Vdelta2 T cells expansion efficiencies by zoledronic acid and gammadelta TCR monoclonal antibody in vitro].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
December 2012
Objective: To find out the more efficient induction method through investigating the expansion efficiencies of HIV-infected patients' Vdelta2 T cells induced by zoledronic acid (Zol) or gammadelta TCR monoclonal antibody (mAb).
Methods: 38 healthy control subjects (HC group) and 65 HIV infected patients (HIV group) were enrolled in this research. Peripheral blood mononuclear cells (PBMCs) of individuals were stimulated by Zol or gammadelta TCR mAb respectively for 14 days at 2.
[Analysis for post-transplant changes of peripheral lymphocyte subsets in liver transplant receptors with HBV infection].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
July 2011
Aim: To investigate the characters and changes of peripheral lymphocyte subsets and cytokines in liver transplant receptors with HBV infection in short phases after liver transplantation, and to provide evidences for monitoring post-transplant immune condition of liver transplant receptors.
Methods: Peripheral lymphocyte subsets and cytokine levels in pre- and post- transplant 12 h, 3 d, 10 d, 30 d, 60 d of 20 cases of patients with HBV-associated severe hepatic diseases were investigated and analyzed, and were compared respectively with those of 22 cases of healthy adults as control (HC) with flow cytometry (FCM) and ELISA.
Results: The patients' accounts of peripheral lymphocyte subsets before liver transplantation were lower than those of HC significantly, but the accounts decreased significantly after transplantation 12 h.